Gongji Pregnancy Endocrine Cohort
Serological, Metabolomic, and Genomic Studies of Endocrine Disorders in Pregnancy
This project will try to see how genes, lifestyle, and medications relate to gestational diabetes and thyroid problems and their effects on pregnancy and the first year after birth for women planning pregnancy, pregnant, or within one year postpartum.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | Female |
| Sponsor | Shanghai General Hospital, China Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Trial ID | NCT07125885 on ClinicalTrials.gov |
What this trial studies
This is an observational cohort combining prospective and retrospective data collection at Shanghai General Hospital. Researchers will collect genetic information, lifestyle factors, and records of any drug treatments, then link those data to the occurrence and progression of gestational endocrine conditions and to pregnancy and postpartum maternal‑infant outcomes. Eligible participants are adult women planning pregnancy, currently pregnant, or within one year after delivery who sign informed consent. No investigational interventions are given as part of the study; participants undergo follow‑up and data collection only.
Who should consider this trial
Good fit: Women aged 18 or older who are preparing for pregnancy, currently pregnant, or within one year after giving birth and who consent to follow‑up are ideal candidates.
Not a fit: Pregnant women with severe organic diseases or serious mental illness, individuals unable to communicate normally, or those unwilling to cooperate are excluded and would not participate or benefit from this study.
Why it matters
Potential benefit: If successful, the study could help identify genetic and modifiable risk factors to guide prevention and personalized management and reduce adverse pregnancy and postpartum outcomes.
How similar studies have performed: Other cohort studies have linked genetics, lifestyle, and treatment patterns to gestational diabetes and thyroid disorders and have produced useful risk markers, though each new cohort adds population‑specific detail.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women preparing for pregnancy or pregnant women or within 1 year after giving birth * Age ≥ 18 years old * Signed the informed consent form to voluntarily enroll in the management follow-up Exclusion Criteria: * Individuals who are unable to communicate normally and those who are unwilling to cooperate * Pregnant women with severe organic diseases or mental illnesses * Any condition deemed by the investigator to affect eligibility for the study
Where this trial is running
Shanghai, Shanghai Municipality
- Shanghai General Hospital, China — Shanghai, Shanghai Municipality, China (Recruiting)
Study contacts
- Study coordinator: Yufan Wang, PhD
- Email: yyffwang@sina.com
- Phone: (+86) 021-63240090
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.