Glycosylated ferritin testing for adult Still's disease and macrophage activation syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study collecting serum from adults with suspected HLH/macrophage activation syndrome or adult-onset Still's disease and from control groups with sepsis, autoimmune inflammation, hepatic necrosis, or hematologic malignancy. The study measures the percentage of glycosylated ferritin and characterizes ferritin glycoforms, including mass spectrometry analysis. Investigators will compare glycosylated ferritin levels and glycoform patterns between diagnostic groups to determine diagnostic performance. Results will be correlated with clinical and laboratory diagnostic criteria recorded by treating physicians.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Suspicion of sepsis, macrophagic activation syndrome, Still's disease or hyperferritinemia (malignant disease, hepatic cytolysis)

Exclusion Criteria:

* Normal ferritin level

Where it's running

• Brugmann University Hospital
  Brussels, Belgium Recruiting

Study contacts

• Study coordinator: Francis Corazza, MD, PhD
• Email: francis.corazza@ulb.ac.be
• Phone: 32-2-4772506

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.