GlycoQuest: an AI-powered CGM game for kids with type 1 diabetes and their families

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial tests GlycoQuest, a digital therapeutic that blends continuous glucose monitoring data with an adaptive, child-facing game and parent–child collaboration. The game uses real-time glucose patterns to tailor learning pathways and in-game scenarios, aiming to improve self-management skills and reduce diabetes distress. The study also includes psychosocial content addressing fear of hypoglycemia, stigma, illness acceptance, and family communication, along with practical modules on insulin safety and carbohydrate estimation. Participants are children with recent type 1 diabetes diagnosis (within 3 months) and their primary caregivers, who will engage with the CGM-linked platform over the first year after diagnosis. The primary question is whether this personalized digital intervention can improve glycemic outcomes and family functioning compared with standard education alone.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Child or adolescent aged 6 to 17 years at enrollment.
* Diagnosis of type 1 diabetes confirmed by a pediatric endocrinologist according to standard clinical criteria.
* Type 1 diabetes diagnosed within the previous 3 months.
* Primary caregiver aged 18 years or older willing to participate as part of a parent-child dyad.
* Current use of continuous glucose monitoring or willingness to initiate CGM as part of standard diabetes care.
* Household access to a compatible smartphone or tablet, or willingness to use a study-provided device if available.
* Ability of child and caregiver to engage with study procedures and digital intervention content.
* Caregiver able to provide written informed consent.
* Child able to provide age-appropriate assent.

Exclusion Criteria:

* Type 1 diabetes diagnosed more than 3 months before enrollment.
* Concurrent participation in another intensive diabetes behavioral intervention trial.
* Significant developmental, intellectual, visual, motor, or psychiatric condition that, in the opinion of the clinical team, would preclude meaningful engagement with the digital game interface or study procedures.
* Acute psychiatric instability or safety concern requiring urgent specialist intervention.
* Planned transfer to a different diabetes care provider within 6 months.
* Absence of internet access that cannot be addressed by study support.

Where it's running

• Shifa International hospital
  Lahore, Punjab Province, Pakistan Recruiting

Study contacts

• Study coordinator: Nadia Hussain, MD, PhD
• Email: nadia.hussain@aau.ac.ae
• Phone: 0505440153

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.