Clinical trial Recruiting at 1 site Observational Ages 18 and up

Glomerulonephritis Kidney Transplant Recipient Cohort (China)

Official title: China Glomerulonephritis Kidney Transplant Recipient Cohort: A Prospective Multicenter Observational Study

Run by AstraZeneca · NCT07783737 · Data updated 2026-11-12

This study will follow adults with glomerulonephritis who are scheduled for kidney transplant in China to see how GN recurs after transplant and how the primary disease progresses over 3 years.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorAstraZeneca
Industry-sponsored
Locations9 sites (Beijing, Beijing Municipality and 8 other locations)
StatusRecruiting
StartedOctober 1, 2026
Main results expectedAugust 29, 2030
Study endsAugust 29, 2030
Registry record updatedOctober 21, 2026
Trial IDNCT07783737 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) with primary glomerulonephritis scheduled for kidney transplantation.

Probably not a fit

Patients who do not have GN recurrence or whose management is standard across sites may not see direct benefits from the study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicenter, prospective observational study enrolling about 300 adults with confirmed glomerulonephritis before kidney transplantation. Participants will be followed from screening through kidney transplantation and for 3 years afterward, with visits every 3 months in year 1 and every 6 months in years 2–3 (eight total visits across sites in Beijing, Guangzhou, and Nanning). The study will collect data on GN recurrence, post-transplant outcomes, and treatment of the primary disease to inform future research, drug development, and translational work. No interventions are assigned; the study observes real-world clinical practice across 10 centers in China.

Why it matters

Potential benefit: If successful, findings could clarify GN recurrence patterns after transplantation and help optimize post-transplant management for GN patients.

How similar studies have gone: Prior observational work in transplant populations has shown value in understanding disease recurrence and outcomes, though this specific GN pre-transplant cohort is relatively novel in China.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years.
* Diagnosed with primary GN based on clinical guidelines and/or expert consensus
* Successfully matching completed and confirmed to be scheduled for kidney transplantation.

Exclusion Criteria:

* History of organ transplantation or planned multiple organ transplantation.
* Complicated with malignancy.
* Failure to undergo kidney transplantation for any reason.
* Unable to provide written informed consent form (ICF).

Where it's running

  • Research Site
    Nanning, Guangxi, China
    Recruiting
  • Research Site
    Beijing, Beijing Municipality, China
    Not yet recruiting
  • Research Site
    Guangzhou, Guangdong, China
    Not yet recruiting
  • Research Site
    Zhengzhou, Henan, China
    Not yet recruiting
  • Research Site
    Wuhan, Hubei, China
    Not yet recruiting
  • Research Site
    Yantai, Shandong, China
    Not yet recruiting
Show 3 more locations
  • Research Site
    Shanghai, Shanghai Municipality, China
    Terminated
  • Research Site
    Taiyuan, Shanxi, China
    Not yet recruiting
  • Research Cite
    Tianjin, Tianjin Municipality, China
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Browse more
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.