Global analysis of cardiovascular risk factors and their impact on health
Predicting Cardiovascular Risk by Geographical Region and Sex Using Classical Cardiovascular Risk Factors
This study looks at how common heart disease risk factors like weight, blood pressure, and smoking affect people's heart health and overall survival to help create better prevention strategies worldwide.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Universitätsklinikum Hamburg-Eppendorf Academic / other |
| Locations | 1 site (Hamburg, Free and Hanseatic City of Hamburg) |
| Trial ID | NCT05466825 on ClinicalTrials.gov |
What this trial studies
The Global Cardiovascular Risk Consortium (GCVRC) is an international collaboration that aggregates individual-level data from over 2 million participants across 133 cohorts in 39 countries. This observational study focuses on classical cardiovascular risk factors such as body mass index, systolic blood pressure, non-high-density lipoprotein cholesterol, smoking, and diabetes, examining their effects on cardiovascular disease and all-cause mortality. By analyzing this extensive data, the GCVRC aims to develop region-specific strategies for cardiovascular disease prevention and treatment, enhancing global cardiovascular health outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 18 and older with available data on classical cardiovascular risk factors.
Not a fit: Patients with a history of cardiovascular disease at baseline will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for preventing cardiovascular disease and reducing mortality worldwide.
How similar studies have performed: Previous studies have shown success in understanding cardiovascular risk factors, making this approach a continuation of established research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Population-based individual-level data with available information on the classical cardiovascular risk factors including body-mass index, systolic blood pressure, non-high-density lipoprotein cholesterol, current smoking, and diabetes, as well as the outcomes of interest. Exclusion Criteria: * Participants with age below 18 years * No information on the outcome of interest * No information on the exposure of interest (CVD risk factors) * History of CVD at baseline
Where this trial is running
Hamburg, Free and Hanseatic City of Hamburg
- University Medical Center Hamburg-Eppendorf — Hamburg, Free and Hanseatic City of Hamburg, Germany (Recruiting)
Study contacts
- Study coordinator: Prof. Dr. med. Stefan Blankenberg
- Email: s.blankenberg@uke.de
- Phone: +49 (0)40 741056800
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.