Giving prescription glasses to improve vision and thinking in rural older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional project provides free prescription near and/or distance glasses to eligible rural older adults and compares their cognitive change over 36 months with a comparison group that does not receive refractive correction. Eligible participants are community-dwelling residents aged 60–79 in Ya'an, Sichuan, who have correctable vision impairment and normal baseline cognition and hearing by C-MMSE cutoffs. Cognitive decline rates will be measured repeatedly over 36 months and the analysis will include cost-effectiveness of the glasses intervention. The work is delivered through local community health service centers and focuses on scalable, low-cost vision correction.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Older adults who meet all of the following criteria will be eligible to participate in this study:

  * Registered as a rural resident (holding rural household registration);
  * Age from 60 to 79 years at the time of enumeration;
  * Resident in the household for \> = 3 months and planning to reside in the local area for the trial duration;
  * Distance vision impairment (VI, presenting visual acuity \[VA\] \< 6/12 in the better-seeing eye and improving to ≥ 6/7.5 or better in either eye with spectacle correction) and/or near VI (presenting near VA \< 6/12 at 40 cm when measured binocularly and improving to ≥ 6/7.5 or better in either eye with near correction);
  * Independent mobility with or without the support of a walking stick;
  * Chinese version of the Mini-Mental State Examination (C-MMSE) score above the following cut-offs (out of 30): \>17 for illiterate participants, \>20 for those with primary school education, \>22 for those with junior high school education, and \>23 for those with high school education or above.
  * Willingness to participate, to be randomized to either study group, and to adhere to the protocol

Exclusion Criteria:

* Presence of glaucoma or visually significant cataract, or a history of surgical treatment for these or other major ocular conditions;
* Consistent use of prescription spectacles and/or hearing aids;
* Serious medical illness likely to result in loss to follow-up. Those less severely affected by conditions such as hypertension and/or diabetes will be eligible;
* Failure on the whispered voice hearing screening test in the better ear (unable to repeat \> = 3 out of 6 words whispered from behind the participant at a distance of 50 cm);

Where it's running

• Community health service centers
  Ya'an, Sichuan, China Recruiting

Study contacts

• Study coordinator: Yuju Wu
• Email: yujuwu@scu.edu.cn
• Phone: 86+18382096899

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.