Geriatric intervention for frail patients with advanced GI cancers receiving palliative chemotherapy
Official title: Effect of Geriatric Intervention in Frail Patients with Gastric, Biliary, and Pancreatic Cancer Receiving Palliative Chemotherapy
Run by Chang Gung Memorial Hospital · NCT06040801 · Data updated 2026-11-12
This study is testing whether special support for older patients with advanced stomach, bile duct, or pancreatic cancer can help them feel better and get the most out of their chemotherapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 138 (estimated) |
| Sponsor | Chang Gung Memorial Hospital Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Taoyuan, Taiwan) |
| Status | Recruiting |
| Started | December 1, 2021 |
| Main results expected | July 31, 2026 |
| Study ends | July 31, 2026 |
| Registry record updated | February 13, 2025 |
| Trial ID | NCT06040801 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients aged 65 or older with metastatic or unresectable gastric, biliary, or pancreatic cancer who can provide informed consent.
✕Probably not a fit
Patients with cognitive impairments or those receiving concurrent anticancer treatments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on elderly patients aged 65 and older who have metastatic or unresectable gastric, biliary, and pancreatic cancers. It aims to assess the impact of frailty intervention measures on the outcomes of these patients receiving palliative chemotherapy. The study addresses the challenges faced by elderly patients, including concerns about treatment toxicity and comorbidities, which often lead to under-treatment. By implementing a comprehensive geriatric assessment, the study seeks to optimize chemotherapy administration and improve quality of life for this vulnerable population.
Why it matters
Potential benefit: If successful, this intervention could enhance the quality of life and survival outcomes for elderly patients with advanced GI cancers.
How similar studies have gone: While there is limited data on this specific intervention, similar approaches in geriatric oncology have shown promise in improving treatment outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged sixty-five or older with metastatic or unresectable gastric, biliary, and pancreatic cancer. * The patient must sign the informed consent form. * Estimated survival period of more than 3 months. * Conscious and able to communicate verbally or in writing, and willing to cooperate with invasive procedures. Exclusion Criteria: * Patients with cognitive impairment or unable to cooperate with the interventional procedures as determined by the clinical physician. * Patients receiving concurrent other anticancer treatments (radiation or surgery). * Patients with multiple types of cancer requiring simultaneous treatment. * Patients who have previously participated in this study during a prior chemotherapy regimen.
Where it's running
-
Chang Gung Memorial Hospital
Taoyuan, Taiwan, Taiwan Recruiting
Study contacts
- Study coordinator: Wen-Chi Chou, M.D.
- Email: f12986@cgmh.org.tw
- Phone: +886328-1200
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.