Clinical trial Recruiting at 1 site Interventional Ages 65 and up

Geriatric intervention for frail patients with advanced GI cancers receiving palliative chemotherapy

Official title: Effect of Geriatric Intervention in Frail Patients with Gastric, Biliary, and Pancreatic Cancer Receiving Palliative Chemotherapy

Run by Chang Gung Memorial Hospital · NCT06040801 · Data updated 2026-11-12

This study is testing whether special support for older patients with advanced stomach, bile duct, or pancreatic cancer can help them feel better and get the most out of their chemotherapy.

More GI Cancer trials

Quick facts

Study typeInterventional
Ages65 Years and up
SexAll
Enrollment138 (estimated)
SponsorChang Gung Memorial Hospital
Academic / other
Drugs / interventionschemotherapy, radiation
Locations1 site (Taoyuan, Taiwan)
StatusRecruiting
StartedDecember 1, 2021
Main results expectedJuly 31, 2026
Study endsJuly 31, 2026
Registry record updatedFebruary 13, 2025
Trial IDNCT06040801 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients aged 65 or older with metastatic or unresectable gastric, biliary, or pancreatic cancer who can provide informed consent.

Probably not a fit

Patients with cognitive impairments or those receiving concurrent anticancer treatments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on elderly patients aged 65 and older who have metastatic or unresectable gastric, biliary, and pancreatic cancers. It aims to assess the impact of frailty intervention measures on the outcomes of these patients receiving palliative chemotherapy. The study addresses the challenges faced by elderly patients, including concerns about treatment toxicity and comorbidities, which often lead to under-treatment. By implementing a comprehensive geriatric assessment, the study seeks to optimize chemotherapy administration and improve quality of life for this vulnerable population.

Why it matters

Potential benefit: If successful, this intervention could enhance the quality of life and survival outcomes for elderly patients with advanced GI cancers.

How similar studies have gone: While there is limited data on this specific intervention, similar approaches in geriatric oncology have shown promise in improving treatment outcomes.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged sixty-five or older with metastatic or unresectable gastric, biliary, and pancreatic cancer.
* The patient must sign the informed consent form.
* Estimated survival period of more than 3 months.
* Conscious and able to communicate verbally or in writing, and willing to cooperate with invasive procedures.

Exclusion Criteria:

* Patients with cognitive impairment or unable to cooperate with the interventional procedures as determined by the clinical physician.
* Patients receiving concurrent other anticancer treatments (radiation or surgery).
* Patients with multiple types of cancer requiring simultaneous treatment.
* Patients who have previously participated in this study during a prior chemotherapy regimen.

Where it's running

  • Chang Gung Memorial Hospital
    Taoyuan, Taiwan, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.