Geriatric Assessment to support older patients undergoing allo-HSCT
Official title: Geriatric Assessment (GA) for Elderly Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: a Prospective Study.
Run by Peking University People's Hospital · NCT06946654 · Data updated 2026-11-12
This study tests a multidimensional geriatric assessment to see how age, health, and disease factors relate to outcomes for older adults undergoing allogeneic stem cell transplantation.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 55 Years and up |
| Sex | All |
| Enrollment | 176 (estimated) |
| Sponsor | Peking University People's Hospital Academic / other |
| Locations | 1 site (Beijing) |
| Status | Recruiting |
| Started | January 1, 2026 |
| Main results expected | March 31, 2027 |
| Study ends | March 31, 2027 |
| Registry record updated | September 15, 2026 |
| Trial ID | NCT06946654 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients aged 55 and older with hematologic disorders indicated for allo-HSCT and who are willing to provide informed consent.
✕Probably not a fit
Patients without meaningful comorbidity patterns or who are not candidates for allo-HSCT may not derive benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study collects patient, disease, donor, and treatment information to identify risk factors that influence transplant outcomes in elderly patients. It aims to build a comprehensive geriatric assessment model and use it to guide personalized pre-transplant strategies. The analysis considers age, physical function, comorbidities, disease characteristics, donor details, conditioning regimens, graft source, and GVHD prophylaxis. The goal is to reduce transplant-related mortality and improve overall allo-HSCT outcomes in the elderly population. The study is led by Peking University People’s Hospital in Beijing and does not list collaborators.
Why it matters
Potential benefit: If successful, the model could help clinicians tailor transplant planning to reduce risks and improve survival for older patients undergoing allo-HSCT.
How similar studies have gone: Previous work in similar geriatric assessments has shown potential to predict transplant complications, though this specific, comprehensive approach in allo-HSCT elderly patients is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * (a)Age ≥55 years. * (b)Hematologic disorders with established indications for transplantation, including malignant and non-malignant hematologic diseases. (c)Willingness to provide informed consent. Exclusion Criteria: (a)Pregnancy. (b) Uncontrolled active infection. (c) Lack of informed consent. (d)Deemed ineligible for transplantation after investigator assessment
Where it's running
-
Peking University People's Hospital
Beijing, China Recruiting
Study contacts
- Study coordinator: Yuqian Sun
- Email: sunyuqian83@hotmail.com
- Phone: 861088326666
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.