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Genotyping rickettsiosis-causing agents in patients from the Altai Republic

The Surveillance (Non-interventional, Observational) Multicenter Clinical Study of Rickettsiosis

Observational Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation · NCT06162975

This study is trying to find out more about the types of germs that cause rickettsiosis in people from the Altai Republic who have been bitten by ticks.

Quick facts

Study typeObservational
Enrollment2000 (estimated)
SexAll
SponsorGamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Academic / other
Locations24 sites (Chemal, Altai Republic and 23 other locations)
Trial IDNCT06162975 on ClinicalTrials.gov

What this trial studies

This observational clinical study aims to genotype the causative agents of rickettsiosis in biological samples from patients diagnosed or suspected to have tick-borne rickettsioses in the Altai Republic, Russian Federation. The study involves collecting medical histories, disease progression, symptoms, and treatments from participants without any intervention to their routine care. Biological samples such as plasma, serum, and swabs from tick bite sites will be analyzed to identify new rickettsia types and compare these findings with clinical data to establish specific patterns. Informed consent is obtained from all participants or their legal representatives.

Who should consider this trial

Good fit: Ideal candidates include male and female patients of any age with diagnosed or suspected tick-borne rickettsioses.

Not a fit: Patients unwilling to participate in the study will not benefit from the findings.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of rickettsiosis and improve diagnostic accuracy for patients in affected regions.

How similar studies have performed: While there may be similar observational studies, this specific approach to genotyping in the Altai Republic is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

To be included in the study, the subject must meet all the following criteria:

* Written informed consent by the subject (or their legal representative) to participate in the study;
* Men and women of any age, including children, who:

have sought medical care (outpatient or inpatient) with suspected or diagnosed rickettsiosis; or have sought medical care (inpatient) with a history of tick bites and elevated body temperature (at least 37.2 °C lasting at least 48 hours).

Exclusion Criteria:

\- Inability or unwillingness of the subject (or their legal representative) to participate in the study

Where this trial is running

Chemal, Altai Republic and 23 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov → Find more trials like this →
Conditions Rickettsiosis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.