Genotyping rickettsiosis-causing agents in patients from the Altai Republic
Official title: The Surveillance (Non-interventional, Observational) Multicenter Clinical Study of Rickettsiosis
Run by Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation · NCT06162975 · Data updated 2026-11-12
This study is trying to find out more about the types of germs that cause rickettsiosis in people from the Altai Republic who have been bitten by ticks.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Academic / other |
| Locations | 24 sites (Chemal, Altai Republic and 23 other locations) |
| Status | Recruiting |
| Started | April 1, 2023 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | February 19, 2026 |
| Trial ID | NCT06162975 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include male and female patients of any age with diagnosed or suspected tick-borne rickettsioses.
✕Probably not a fit
Patients unwilling to participate in the study will not benefit from the findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational clinical study aims to genotype the causative agents of rickettsiosis in biological samples from patients diagnosed or suspected to have tick-borne rickettsioses in the Altai Republic, Russian Federation. The study involves collecting medical histories, disease progression, symptoms, and treatments from participants without any intervention to their routine care. Biological samples such as plasma, serum, and swabs from tick bite sites will be analyzed to identify new rickettsia types and compare these findings with clinical data to establish specific patterns. Informed consent is obtained from all participants or their legal representatives.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of rickettsiosis and improve diagnostic accuracy for patients in affected regions.
How similar studies have gone: While there may be similar observational studies, this specific approach to genotyping in the Altai Republic is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: To be included in the study, the subject must meet all the following criteria: * Written informed consent by the subject (or their legal representative) to participate in the study; * Men and women of any age, including children, who: have sought medical care (outpatient or inpatient) with suspected or diagnosed rickettsiosis; or have sought medical care (inpatient) with a history of tick bites and elevated body temperature (at least 37.2 °C lasting at least 48 hours). Exclusion Criteria: \- Inability or unwillingness of the subject (or their legal representative) to participate in the study
Where it's running
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Chemal District Hospital
Chemal, Altai Republic, Russia Recruiting -
Center for AIDS Prophylaxis and Treatment
Gorno-Altaysk, Altai Republic, Russia Recruiting -
Choya District Hospital
Gusevka, Altai Republic, Russia Recruiting -
Kosh-Agach District Hospital
Kosh-Agach, Altai Republic, Russia Recruiting -
Mayma District Hospital
Mayma, Altai Republic, Russia Recruiting -
Onguday District Hospital
Onguday, Altai Republic, Russia Recruiting
Show 18 more locations
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Ust-Kan District Hospital
Ust'-Kan, Altai Republic, Russia Recruiting -
Ust-Koksa District Hospital
Ust'-Koksa, Altai Republic, Russia Recruiting -
Ulagan District Hospital
Ust'-Ulagan, Altai Republic, Russia Recruiting -
Altai State Medical University
Barnaul, Altayskiy Kray, Russia Recruiting -
City Hospital No. 5
Barnaul, Altayskiy Kray, Russia Recruiting -
Barnaul Regional Clinical Hospital for Emergency Medical Care No. 2
Barnaul, Altayskiy Kray, Russia Recruiting -
Biysk Central City Hospital
Biysk, Altayskiy Kray, Russia Recruiting -
Regional Infectious Diseases Clinical Hospital named after A.M. Nichoga
Astrakhan, Astrakhan Oblast, Russia Recruiting -
Irkutsk State Medical University
Irkutsk, Irkutsk Oblast, Russia Recruiting -
Irkutsk Regional Infectious Diseases Clinical Hospital
Irkutsk, Irkutsk Oblast, Russia Recruiting -
City Clinical Hospital named after Professor A.M. Voyno-Yasenetsky
Khabarovsk, Khabarovskiy Kray, Russia Recruiting -
Imeni Lazo District Hospital
Pereyaslavka, Khabarovskiy Kray, Russia Recruiting -
Pskov Regional Infectious Diseases Clinical Hospital
Pskov, Pskov Oblast, Russia Recruiting -
Republican Clinical Infectious Diseases Hospital
Abakan, Respublika Khakasiya, Russia Recruiting -
Abakan Interdistrict Clinical Hospital
Abakan, Respublika Khakasiya, Russia Recruiting -
Sayanogorsk Interdistrict Hospital
Sayanogorsk, Respublika Khakasiya, Russia Recruiting -
Infectious Diseases Hospital
Kyzyl, Respublika Tyva, Russia Recruiting -
Yakutia Republican Clinical Hospital
Yakutsk, Sakha, Russia Recruiting
Study contacts
- Principal investigator: Alexey V. Kostarnoy, PhD — Gamaleya Research Center of Epidemiology and Microbiology, Health Ministry of the Russian Federation
- Study coordinator: Petya G. Gancheva
- Email: gancheva87@mail.ru
- Phone: +7 9689069198
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.