Genomic risk assessment program for diverse populations
Deploying a Genomic-medicine Risk Assessment Model for Diverse Primary Care Populations and Settings
This study is testing a new program to help people from diverse backgrounds understand their genetic risks for diseases like heart problems and cancer, making it easier for them to get the care they need.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 750 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Duke University Academic / other |
| Locations | 4 sites (Jacksonville, Florida and 3 other locations) |
| Trial ID | NCT06278883 on ClinicalTrials.gov |
What this trial studies
The GRACE project aims to create a scalable solution for genomic risk assessment and management tailored for low-resource settings. It focuses on developing an implementation framework that can be adapted to various clinical environments, enhancing access to genomic medicine. The project will utilize a Family Health History-driven risk assessment tool and promote family engagement to identify individuals at increased risk for conditions like cardiovascular diseases and cancer. By facilitating genetic testing and cascade screening, the initiative seeks to improve health outcomes and reduce disparities in healthcare access.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who receive primary medical care at participating clinics and can communicate in English.
Not a fit: Patients who have previously undergone genetic counseling or hereditary panel testing may not benefit from this program.
Why it matters
Potential benefit: If successful, this program could significantly enhance access to genomic risk assessments, leading to better health outcomes and reduced healthcare costs for diverse populations.
How similar studies have performed: Other studies have shown promise in implementing genomic medicine in diverse populations, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Receiving primary medical care in one of the 5 participating clinics * Age 18 years or older * Able to read and communicate in English * Able to provide written and verbal informed consent * Willing to use the Internet Exclusion Criteria: * Anyone not meeting inclusion criteria * Previous genetic counseling and/or previous hereditary panel testing
Where this trial is running
Jacksonville, Florida and 3 other locations
- UF Health Family Medicine - Lem Turner — Jacksonville, Florida, United States (Completed)
- UF Health Family Medicine - Commonwealth — Jacksonville, Florida, United States (Recruiting)
- UF Health Augustine Oaks — Jacksonville, Florida, United States (Completed)
- UF Health Oakleaf — Orange Park, Florida, United States (Recruiting)
Study contacts
- Principal investigator: Lori Orlando, MD — Duke University
- Study coordinator: Alexander S Parker, PhD
- Email: alexander.parker@jax.ufl.edu
- Phone: (904) 244-9478
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.