Genetic profiling of children with alpha thalassemia at Sohag University Hospital
Genetic Profile of Alpha Thalassemia Children at Sohag University Hospital .
This study looks at the genetic makeup of children with alpha thalassemia at Sohag University Hospital to better understand how the condition affects them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 0 Days to 18 Years |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06591936 on ClinicalTrials.gov |
What this trial studies
This observational study aims to analyze the genetic profile of children diagnosed with alpha thalassemia at Sohag University Hospital. It focuses on determining the prevalence and molecular characteristics of the disorder, which is marked by reduced synthesis of alpha-globin. The study seeks to provide insights into the mechanisms underlying the phenotypic variability observed in affected individuals.
Who should consider this trial
Good fit: Ideal candidates for this study are children aged 0-18 years who are suspected of having alpha thalassemia and exhibit microcytic hypochromic anemia not due to iron deficiency or beta thalassemia.
Not a fit: Patients over 18 years old or those who are healthy and free from any chronic hematological disease will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of alpha thalassemia, leading to improved diagnosis and management strategies for affected children.
How similar studies have performed: While this study focuses on a specific population, similar studies have shown success in understanding genetic disorders, suggesting potential for valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Acase suspecteed of alpha thalassemia * age between 0-18years * micocytic hypochromic anemia not iron deficiency anemia or Beta thalassemia Exclusion Criteria: * Age more than 18 years * healthy children free from any chronic hematological disease * micocytic hypochromic anemia either iron deficiency anemia or Beta thalassemia
Where this trial is running
Sohag
- Sohag University Hospital — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: marwa M abdelraheem, resedent doctor
- Email: Marwa.Abdelraheem2015@med.sohag.edu.eg
- Phone: 01152389379
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.