Genetic analysis of keloids
Identification of Genetic Variants That Contribute to Keloid Formation in Families and Isolated Cases.
This study is trying to find out if certain genes play a role in how keloids form and grow, by looking at saliva samples and scar tissue from people with these scars.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 7000 (estimated) |
| Sex | All |
| Sponsor | UConn Health Academic / other |
| Locations | 1 site (Farmington, Connecticut) |
| Trial ID | NCT01619553 on ClinicalTrials.gov |
What this trial studies
This study aims to identify the genetic factors contributing to the development of keloids, which are abnormal scars that grow beyond the original wound site. Participants will provide saliva samples and information about their keloids, and if they undergo surgery, scar tissue may also be collected for analysis. The research will focus on isolating DNA and performing genetic analyses to uncover variations that may influence keloid formation and severity. The ultimate goal is to enhance understanding of the genetic basis of keloids and their behavior.
Who should consider this trial
Good fit: Ideal candidates include individuals with keloids and unaffected family members of keloid patients.
Not a fit: Patients without keloids or those not related to a keloid-affected family may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better prevention and treatment strategies for keloids.
How similar studies have performed: While genetic studies on keloids are limited, similar approaches in other genetic conditions have shown promise in identifying causative factors.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * keloids; * unaffected individuals only if part of a participating keloid family Exclusion Criteria: * no keloids; * unaffected individuals only as part of a participating keloid family
Where this trial is running
Farmington, Connecticut
- University of Connecticut Health Center (UCHC) — Farmington, Connecticut, United States (Recruiting)
Study contacts
- Principal investigator: Ernst Reichenberger, PhD — UConn Health
- Study coordinator: Ernst Reichenberger, PhD
- Email: reichenberger@uchc.edu
- Phone: 866-512-9897
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.