Genetic analysis of brain blood vessel malformations

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on understanding the genetic, molecular, and cellular mechanisms behind cerebral and medullary arteriovenous malformations (AVMs). It aims to investigate the influence of genetic mutations on the prognosis of AVMs, particularly in cases that are not linked to hereditary conditions. Patients with diagnosed vascular malformations will provide blood samples for genetic analysis, which may help clarify the role of specific mutations in AVM development and outcomes. The study is conducted at the Hôpital Fondation Adolphe de Rothschild in Paris.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient with a vascular malformation of the cerebral or medullary identified on diagnostic imaging (angio-CT, angio-MRI or diagnostic angiography) for which clinical monitoring alone or intervention (endovascular treatment, surgery or radiosurgery) is planned in the centres participating in the research.

Exclusion Criteria:

* Pregnant, parturient or breastfeeding woman

Where it's running

• HOPITAL FONDATION Adolphe de ROTHSCHILD
  Paris, France Recruiting

Study contacts

• Principal investigator: Stanislas Smajda, MD — Fondation Ophtalmologique Adolphe de Rothschild
• Study coordinator: Stanislas Smajda, MD
• Email: ssmajda@for.paris
• Phone: 0148036454

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.