Gender-affirming hormone therapy for transgender individuals in China

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather data on the physical and psychological effects of gender-affirming hormone therapy (GAHT) among transgender individuals in China. Participants seeking GAHT will be enrolled from a major transgender medical center and will undergo interviews and evaluations regarding their life experiences, gender identity, and health conditions. The study will follow participants for up to 12 months, assessing their mental and physical health before and during the hormone therapy. The findings aim to fill the gap in knowledge regarding transgender medical care in China.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Transgender men and women
* Meet criteria of Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) for gender dysphoria
* Aged between 18 to 40 years
* People desire to start the GAHT
* No previous history of gender-affirming interventions
* Having full ability to make informed consent
* Dextromanual

Exclusion Criteria:

* Disorders of sex development
* Who has fertility demand but have not made fertility preservation
* With contradictions of GAHT
* Comorbid diseases are not under control
* Alcohol or drug abuse
* Hormonal and chromosomal disorders
* History of gender affirming surgery
* Current psychiatric disorders
* History of brain trauma or neurological pathologies
* Current use of medications with psychotropic effects within two weeks (antipsychotic or antiepileptic agents, lithium, benzodiazepines or opioid analgesics)
* Claustrophobia
* Implanted metal and medical devices (pacemakers, ceramic teeth, etc.),
* Tattoos or eyebrow tattooing (heavy metal dye)

Where it's running

• Peking University Third Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Tianpei Hong, PhD., M.D. — Department of Endocrinology and Metabolism, Peking University Third Hospital
• Study coordinator: Ye Liu, PhD., M.D.
• Email: yeliumed@bjmu.edu.cn
• Phone: +86-10-82265025

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Swiss prospective cohort of transgender and gender-diverse people

  This project tests which social, medical, and biological factors are linked to health and well-being in transgender and gender-diverse people in Switzerland who are starting, undergoing, or have stopped gender-affirming care.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.