Gender-affirming care and mental health: long-term effects on quality of life, work ability, and healthcare use

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

GLOW is a longitudinal, mixed-methods program following adults referred to the NHV Gender Dysphoria Clinic in Region Skåne. It combines repeated self-reported measures of mental health, gender congruence, quality of life, and work capacity with linked national registry data on healthcare use, prescriptions, socio-economic indicators, and mortality. The study also conducts in-depth qualitative interviews and uses standardized clinical data collection across the clinic to capture medical and social context over time. Stakeholders including clinicians and patient advocacy organizations are involved to ensure the research addresses real-world priorities.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All adults (18+) referred to the NHV clinic for gender dysphoria assessment in Region Skåne.

Exclusion Criteria:

* Inability to read/write Swedish
* Protected identity status

Where it's running

• The Gender Dysphoria Clinic at Skåne University Hospital, Malmö, Sweden
  Malmö, Malmö, Sweden Recruiting

Study contacts

• Study coordinator: Emma Claesdotter-Knutsson, MD; Ass prof
• Email: emma.claesdotter-knutsson@regionskane.se
• Phone: +46768871765

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.