Gastrointestinal stimulation to treat bowel paralysis after major surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the use of gastrointestinal stimulation with a pacemaker to reduce the duration of postoperative ileus in patients undergoing major abdominal surgery for metastatic colorectal cancer, appendiceal cancer, or pseudomyxoma peritonei. Participants will receive either active stimulation or a control treatment during their recovery. The study aims to determine if stimulating the gastrointestinal tract can lead to faster bowel recovery post-surgery. Patients will track their bowel movements daily to assess the effectiveness of the intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients planned for elective cytoreductive surgery with or without heated intraperitoneal chemotherapy due to either colorectal or appendiceal cancer or with peritoneal metastases or due to pseudomyxoma peritonei
* Written and orally informed consent
* Over 18 years of age

Exclusion Criteria:

* Previous upper gastric or esophageal resection
* History of difficulties in swallowing or gastrointestinal stenosis
* Implanted or portable electrical medical device e.g. cardiac pacemaker, defibrillator or infusion pump etc.
* Pregnant or breast-feeding women

Where it's running

• Aarhus University Hospital
  Aarhus, Denmark Recruiting

Study contacts

• Principal investigator: Jonas Funder, MD, PhD — Aarhus University Hospital
• Study coordinator: Anne K Martensen, MD
• Email: anmate@rm.dk
• Phone: +45 30595095

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.