Gastrocnemius myofascial release for women with knee osteoarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional trial compares gastrocnemius myofascial release plus conventional physical therapy to sham gastrocnemius myofascial release plus conventional physical therapy in females with knee osteoarthritis. Participants receive real or sham gastrocnemius MFR three times per week for four weeks while both groups undergo standard physical therapy. Outcomes measured include pain, physical function, foot posture, and knee disability assessed before and after the intervention. The single-center trial is conducted at the Faculty of Physical Therapy, Cairo University and enrolls women with radiographic grade II–III knee osteoarthritis, BMI ≤35, and baseline pain of at least 4/10.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients' ages ranged between 45 and 55 years .
* BMI ≤35
* Patients with a diagnosis of primary KOA according to the American College of Rheumatology classification at the screening visit .
* Onset of symptomatic knee osteoarthritis of ≥3 months
* Patients with grade II and III OA of the Kellgren and Lawrence system for classification of osteoarthritis .
* At least one active trigger point in GM
* If both knees were diagnosed as OA, the most affected one was selected.
* Current pain intensity on the Visual Analogue Scale (VAS) ≥4/10.
* Subjects have sufficient cognition that enables them to understand the requirements of the study, comply with the study procedures, and visit schedule.
* Diagnostic Criteria of KOA

A diagnosis of knee osteoarthritis was made when knee pain is present, plus Osteophytes on radiographs, plus at least 1 of the following 3:

* Age \> 50 years
* Morning stiffness \< 30 minutes
* Crepitus on active motion

Exclusion Criteria:

* Patients with any previous knee surgeries or lower limb fractures.
* Chronic inflammatory diseases such as rheumatoid arthritis.
* Signs of moderately significant knee synovitis include a warm and swollen (red) knee
* History and/or physical examination findings compatible with knee internal derangement (e.g, positive Thessaly test).
* Pregnancy
* Patients who had undergone arthroscopy or treatment with intra-articular hyaluronic acid during the previous 6 months .
* Use of NSAIDs one week before the screening visit .
* Orthopedic diseases, or congenital musculoskeletal deformities, or neurological disorders that may affect or interfere with the therapeutic effect.
* Participated in other intervention studies (strength training program or physiotherapy treatment for knee osteoarthritis) in the current period and the past 6 months .
* Habitual use of psychotropic or narcotic analgesics for ≥1 week within 8 weeks prior to screening .

Where it's running

• Faculty of Physical Therapy, Cairo University
  Giza, Giza Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Hend Hammam Soliman, Bachelor's Degree
• Email: hendhammam18@live.com
• Phone: +201008380834

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.