Gamified somatosensory and narrative rehabilitation to improve thinking and social skills in hospitalized adults with schizophrenia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Hospitalized patients with ICD-10 schizophrenia aged 18–45 who are clinically stable are randomly assigned to receive routine inpatient psychiatric rehabilitation with or without additional gamified digital interventions. The intervention group receives somatosensory cognitive games and interactive narrative games three times per week for 30 minutes over 8 weeks, while the control group receives standard care alone. Clinical assessments are performed at baseline, immediately after 8 weeks, and periodically during a 24-month follow-up to track cognitive, psychosocial, and functional outcomes. The protocol was approved by the Institutional Review Board at Shanghai Mental Health Center and participants must be able to use a smartphone or tablet independently.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Registered in the Shanghai Mental Health Information Management System and hospitalized in the designated district-level mental health center wards;
2. Schizophrenia patients meeting the diagnostic criteria of schizophrenia in the International Classification of Diseases (ICD-10);
3. 18 - 45 years old;
4. Good self-care ability;
5. Clinically stable (without acute exacerbation) for at least 1 week before enrollment, with a stable dose of antipsychotic drugs or other concomitant psychotropic drugs for at least 1 week;
6. No hand disabilities, and can use mobile phones or tablets normally;
7. Have a primary school education or above;
8. Normal vision and hearing, or within the normal range after correction;
9. Own and be able to independently use a smart phone or other electronic devices;
10. Patients and their families have given informed consent to this study, and voluntarily cooperate to participate in the intervention and sign the informed consent form.

Exclusion Criteria:

1. not reside in Shanghai after discharge;
2. suffering from serious physical or brain organic diseases;
3. comorbid with other psychotic disorders.

Where it's running

• Shanghai Mental Health Center
  Shanghai, China Recruiting

Study contacts

• Principal investigator: Jun Cai — Shanghai Mental Health Center
• Study coordinator: Weibo Zhang
• Email: zhangweibo600@163.com
• Phone: 86-13764694223

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.