Gait training with blood flow restriction for children with cerebral palsy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study evaluates the feasibility and effects of a 10-week gait training program combined with blood flow restriction (BFR) on walking speed in children aged 8 to 18 with bilateral spastic cerebral palsy. Participants will engage in treadmill sessions three times a week, gradually increasing their walking speed while under BFR conditions. The study aims to assess both the tolerability of the intervention and its impact on improving walking efficiency and endurance in this population. The program includes a week of habituation without BFR followed by nine weeks of training with BFR.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 8 to 18 with bilateral spastic cerebral palsy
* Patient with functional level II or III according to the Gross Motor Function Classification System (GMFCS)
* Patient able to assess pain with NRS-11
* Patient able to walk on a treadmill without body weight support, with or without technical aids
* Patient able to perform the 10-meter walk test
* No skin pathology at the pressure cuff application site (eczema, inflammatory scarring, etc.)
* Patient affiliated to or benefiting from a social security scheme
* Informed consent, dated and signed by parents or guardians (if a minor) or by the patient (if of age), to participate in the study;

Exclusion Criteria:

* Patients who have undergone surgical treatment or intramuscular injections of botulinum toxin in the lower limbs within the last 3 months
* Patients with a history of arterial hypertension, thrombo-embolic events, thrombophilia or cancer.
* Patient with insufficient understanding of the French language;
* Opposition of the patient (child or adolescent);
* Pregnant, breast-feeding or parturient women;
* Persons deprived of their liberty by judicial or administrative decision;
* Persons under compulsory psychiatric care;
* Persons under legal protection

Where it's running

• Les Capucins
  Angers, France Recruiting
• University Hospital, Angers
  Angers, France Not yet recruiting

Study contacts

• Principal investigator: Adélie Christiaens — University Hospital, Angers
• Study coordinator: Adélie Christiaens
• Email: adelie.christiaens@univ-angers.fr
• Phone: 2 41 35 18 04

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.