Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Gait training program for stroke survivors who can't walk

Official title: To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors

Run by University of Kansas Medical Center · NCT06247553 · Data updated 2026-11-12

This study is testing a new walking program on a treadmill for stroke survivors who can't walk to see if it helps them get healthier compared to doing leg cycling exercises while sitting.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment72 (estimated)
SponsorUniversity of Kansas Medical Center
Academic / other
Locations1 site (Kansas City, Kansas)
StatusRecruiting
StartedFebruary 2, 2024
Main results expectedAugust 31, 2027
Study endsSeptember 1, 2027
Registry record updatedAugust 1, 2025
Trial IDNCT06247553 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 80 who were independent walkers before their stroke and are currently unable to walk independently due to chronic stroke effects.

Probably not a fit

Patients with severe musculoskeletal disorders, uncontrolled high blood pressure, or those currently engaged in similar walking training may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of a novel gait training program for non-ambulatory chronic stroke survivors. Participants will engage in treadmill walking with partial body-weight support, while a control group will perform sitting leg cycling exercises. The study will measure improvements in cardiovascular health indicators such as resting heart rate, systolic blood pressure, and A1c levels over an 8-week period. The goal is to determine if gait training offers superior benefits compared to traditional cycling exercises.

Why it matters

Potential benefit: If successful, this program could significantly enhance cardiovascular health and overall quality of life for non-ambulatory stroke survivors.

How similar studies have gone: Previous studies have shown positive outcomes for gait training in stroke rehabilitation, indicating potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* must be 18 to 80 years old
* male or female
* independent ambulation before stroke
* able to understand and follow verbal commands in English
* have physicians' approval for exercise
* be in a stable medical condition
* must be after the first stroke
* unable to walk independently
* in the chronic stage (at least 6 months after stroke onset)

Exclusion Criteria:

* musculoskeletal or other disorders that prevent the participant from participating in the exercise
* blood pressure higher than 200/110 mm Hg
* diagnosis of severe depression
* functionally restricted passive movement in the major joints of lower limbs
* unable to speak or understand English
* unable to travel to the Research Laboratory
* currently participate in other walking training using treadmill with or without a body-weight support system
* body weight greater than 400 lbs

Where it's running

  • University of Kansas Medical Center
    Kansas City, Kansas, United States
    Recruiting

Study contacts

  • Principal investigator: Wen Liu, PhD — University of Kansas Medical Center
  • Study coordinator: Carrie Bailey, MA
  • Email: cbailey8@kumc.edu
  • Phone: 402-709-8841

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  • Remote Ischaemic Conditioning for Fatigue After Stroke 2

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.