GABA's effects on ADHD and seizures in children with epilepsy

Effect of Gamma Aminobutyric Acid on ADHD and Seizures in Children With Epilepsy.

Phase 4 Interventional Tanta University · NCT04144439

This study is testing if GABA can help reduce seizures and improve ADHD symptoms in children who have both epilepsy and ADHD.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment30 (estimated)
Ages4 Years to 18 Years
SexAll
SponsorTanta University Academic / other
Locations1 site (Tanta)
Trial IDNCT04144439 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of Gamma aminobutyric acid (GABA) on children diagnosed with both epilepsy and Attention Deficit Hyperactivity Disorder (ADHD). The research aims to evaluate how GABA may influence the frequency of seizures and ADHD symptoms in this population. By focusing on children who experience both conditions, the study seeks to provide insights into potential therapeutic benefits of GABA. The methodology involves administering GABA and monitoring its effects on seizure activity and ADHD behaviors.

Who should consider this trial

Good fit: Ideal candidates for this study are children who have been diagnosed with both epilepsy and ADHD.

Not a fit: Patients with epilepsy who do not have ADHD may not receive any benefit from this study.

Why it matters

Potential benefit: If successful, this study could offer a new treatment option for managing ADHD symptoms and seizure frequency in children with epilepsy.

How similar studies have performed: While there is limited data on the specific use of GABA for this dual condition, similar studies exploring GABA's effects on neurological disorders have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Epilepsy
* ADHD

Exclusion Criteria:

* Epilepsy without ADHD

Where this trial is running

Tanta

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Epilepsy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.