Functional recovery after lower limb surgery for bone tumors

Functional Recovery in the First Six Postoperative Months of Cancer Patients Undergoing Lower Limb Resection and Reconstruction. An Observational Study

Observational Istituto Ortopedico Rizzoli · NCT06376539

This study looks at how well people recover after surgery for bone tumors in their legs by checking their progress during the hospital stay and again at 3 and 6 months later.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages12 Years to 70 Years
SexAll
SponsorIstituto Ortopedico Rizzoli Academic / other
Locations1 site (Bologna)
Trial IDNCT06376539 on ClinicalTrials.gov

What this trial studies

This observational study aims to track the functional recovery of patients who have undergone resection and reconstruction of lower limbs due to musculoskeletal tumors. It will evaluate patients' clinical recovery at three different time points: during their hospital stay post-surgery, and at 3 and 6 months after the operation. The study will differentiate recovery outcomes based on the anatomical level involved in the surgery, providing a comprehensive overview of the rehabilitation process.

Who should consider this trial

Good fit: Ideal candidates are patients who have undergone lower limb resection and reconstruction due to bone tumors, including those with osteosarcoma and Ewing sarcoma.

Not a fit: Patients who are receiving adjuvant treatment at other centers or who have not activated rehabilitation treatment at the institute will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance rehabilitation strategies and improve functional outcomes for patients recovering from lower limb surgeries due to bone tumors.

How similar studies have performed: While similar studies have explored functional recovery in orthopedic oncology, this specific observational approach focusing on lower limb reconstruction is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All participants undergone lower limb resection and reconstruction with localisation of the disease to the pelvis, femur femur, tibia and foot bones.
* All participants undergone soft tissue resection surgery on the of the lower limb
* All types of oncological diagnoses will be taken considered: osteosarcoma, Ewing and others.

Exclusion Criteria:

* Participants who undergo at our Institute only the surgical treatment while continuing adjuvant treatment at other centres
* Participants for whom no rehabilitation treatment has been activated during adjuvant treatment at our Institute

Where this trial is running

Bologna

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Bone NeoplasmRehabilitationbone tumorphysiotherapyfunctional recovery
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.