Full sternotomy versus J-shaped mini-sternotomy for hemiarch repair of the ascending aorta
Official title: Full Sternotomy Versus J-shaped Mini-sternotomy for Chronic Ascending Aortic Pathology
Run by Tomsk Cardiology Research Institute · NCT07386028 · Data updated 2026-11-12
This compares outcomes of full sternotomy and J-shaped mini-sternotomy in adults having hemiarch repair for an ascending aortic aneurysm to see which approach leads to better early and late recovery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Tomsk Cardiology Research Institute Academic / other |
| Locations | 1 site (Tomsk) |
| Status | Recruiting |
| Started | July 10, 2022 |
| Main results expected | December 2027 |
| Study ends | December 2027 |
| Registry record updated | February 5, 2026 |
| Trial ID | NCT07386028 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with a chronic ascending aortic aneurysm and an ascending aorta diameter greater than 5 cm limited to the ascending aorta who are scheduled for elective hemiarch repair and can give informed consent.
✕Probably not a fit
Patients with acute aortic dissection, urgent/emergent cases, redo aortic surgery, aortic arch involvement, or who require concomitant CABG or left ventricular restoration are excluded and unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional comparison enrolls 200 patients with chronic ascending aortic aneurysm who meet criteria for elective hemiarch repair (ascending aorta >5 cm without arch involvement). One hundred patients will undergo hemiarch repair via full median sternotomy and 100 via a J-shaped mini-sternotomy, with baseline, operative, and postoperative data recorded. Imaging uses ECG-gated CT angiography preoperatively and within two weeks postoperatively with standardized measurements perpendicular to the aortic centerline. Early perioperative outcomes (blood loss, transfusion, lung function, wound complications, morbidity, mortality) and longer-term follow-up outcomes will be compared between the two groups.
Why it matters
Potential benefit: If successful, the mini-sternotomy approach could reduce blood loss, transfusions, respiratory complications and wound problems, enabling faster recovery and shorter hospital stays.
How similar studies have gone: Previous nonrandomized reports of J-shaped mini-sternotomy in aortic surgery have shown reduced blood loss and faster respiratory recovery, but evidence specific to hemiarch repair remains limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Signed informed consent. * Ascending aorta greater than 5 cm without involving the aortic arch Exclusion Criteria: * Acute aortic dissection or urgent/emergent cases. * Redo aortic surgery. * Aortic arch surgery. * Concomitant CABG or left ventricle restoration
Where it's running
-
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia
Tomsk, Russia Recruiting
Study contacts
- Principal investigator: Boris N. Kozlov, MD, PhD — Cardiology Research Institute, Tomsk National Research Medical Center
- Study coordinator: Dmitri S. Panfilov, MD, PhD
- Email: pand2006@yandex.ru
- Phone: +79039130879
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.