Follow-up after COPD exacerbation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study compares patients exposed to an AI-enabled clinical workflow tool (Viz COPD) with a historical control cohort to measure respiratory specialist follow-up and downstream clinical outcomes after an acute COPD exacerbation. The Experimental cohort is collected prospectively with the tool active, the Control cohort is retrospective, and an Exploratory cohort includes both retrospective and prospective data. Primary outcomes include rates and timing of specialist follow-up, rehospitalizations, emergency visits, and mortality within a defined follow-up window. Data are gathered from electronic health records and workflow logs without changing standard clinical treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 40 years or older at the time of arrival to the emergency department.
* Patients with a clinical diagnosis of COPD who present to the emergency department for a moderate or severe COPD exacerbation.
* A moderate exacerbation is defined as an acute exacerbation requiring either systemic corticosteroids (such as intramuscular, intravenous or oral) and/or antibiotics.
* A severe exacerbation is defined as an acute exacerbation requiring hospitalization, or observation for \>24 hours in emergency department/urgent care facility or resulting in death.
* Patients on dual (LABA/LAMA, LABA/ICS, LAMA/ICS) or triple (LABA/LAMA/ICS) long-acting bronchodilator inhalers.

Exclusion Criteria:

* Patients on bronchodilator inhaler monotherapy.
* Patients leaving against medical advice or expiring during hospitalization.
* Patients with tracheostomy.
* Patients with advanced cancer.
* Patients who have received a lung transplant.
* Discharge to hospice care.
* Transfer to another hospital.

Where it's running

• Advocate Lutheran General Hospital
  Park Ridge, Illinois, United States Recruiting
• Cooper University Health Care
  Cherry Hill, New Jersey, United States Recruiting
• Thomas Jefferson University
  Philadelphia, Pennsylvania, United States Recruiting
• Inova Fairfax Hospital
  Falls Church, Virginia, United States Not yet recruiting
• Aurora St. Luke's Medical Center
  Milwaukee, Wisconsin, United States Not yet recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.