Flavonoid-rich Mediterranean diet for people with multiple sclerosis

A Flavonoid-enriched Mediterranean Diet for Multiple Sclerosis

Not applicable Interventional Hasselt University · NCT07033975

This trial will test whether following a flavonoid-rich Mediterranean diet can change disease measures and symptoms in adults with multiple sclerosis who have EDSS scores of 0–6.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages30 Years to 65 Years
SexAll
SponsorHasselt University Academic / other
Locations1 site (Diepenbeek, Limburg)
Trial IDNCT07033975 on ClinicalTrials.gov

What this trial studies

This interventional study asks participants with multiple sclerosis to follow a flavonoid-enriched Mediterranean dietary pattern to see how nutrition affects disease-related parameters. The protocol focuses on a healthier, plant-forward diet high in flavonoids rather than a drug or device intervention. Outcomes will include clinical measures related to MS and likely biomarkers or symptom measures to capture any change during the intervention. The trial enrolls ambulatory participants (EDSS 0–6) without diagnosed digestive pathology and is conducted at Hasselt University in Diepenbeek, Belgium.

Who should consider this trial

Good fit: Ideal candidates are adults with a diagnosis of multiple sclerosis who are ambulatory with EDSS between 0 and 6, have no diagnosed digestive disease, and can attend visits at the Hasselt University site.

Not a fit: People with more advanced disability (EDSS >6), those with diagnosed digestive pathologies, or those unable to follow the dietary program are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, the diet could offer a low-risk way to reduce inflammation or symptoms and slow disease-related changes in people with MS.

How similar studies have performed: Observational studies have linked Mediterranean-style diets with better outcomes in MS, but randomized and flavonoid-specific interventional evidence remains limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Expanded Disability Status Scale (EDSS): 0-6

Exclusion Criteria:

* Diagnosed digestive pathology

Where this trial is running

Diepenbeek, Limburg

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Multiple Sclerosis
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.