Clinical trial Recruiting at 1 site Interventional Ages 30 to 65

Flavonoid-rich Mediterranean diet for people with multiple sclerosis

Official title: A Flavonoid-enriched Mediterranean Diet for Multiple Sclerosis

Run by Hasselt University · NCT07033975 · Data updated 2026-11-12

This trial will test whether following a flavonoid-rich Mediterranean diet can change disease measures and symptoms in adults with multiple sclerosis who have EDSS scores of 0–6.

Quick facts

Study typeInterventional
Ages30 Years to 65 Years
SexAll
Enrollment100 (estimated)
SponsorHasselt University
Academic / other
Locations1 site (Diepenbeek, Limburg)
StatusRecruiting
StartedApril 4, 2023
Main results expectedDecember 2028
Study endsDecember 2028
Registry record updatedJune 24, 2025
Trial IDNCT07033975 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults with a diagnosis of multiple sclerosis who are ambulatory with EDSS between 0 and 6, have no diagnosed digestive disease, and can attend visits at the Hasselt University site.

Probably not a fit

People with more advanced disability (EDSS >6), those with diagnosed digestive pathologies, or those unable to follow the dietary program are unlikely to benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study asks participants with multiple sclerosis to follow a flavonoid-enriched Mediterranean dietary pattern to see how nutrition affects disease-related parameters. The protocol focuses on a healthier, plant-forward diet high in flavonoids rather than a drug or device intervention. Outcomes will include clinical measures related to MS and likely biomarkers or symptom measures to capture any change during the intervention. The trial enrolls ambulatory participants (EDSS 0–6) without diagnosed digestive pathology and is conducted at Hasselt University in Diepenbeek, Belgium.

Why it matters

Potential benefit: If successful, the diet could offer a low-risk way to reduce inflammation or symptoms and slow disease-related changes in people with MS.

How similar studies have gone: Observational studies have linked Mediterranean-style diets with better outcomes in MS, but randomized and flavonoid-specific interventional evidence remains limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Expanded Disability Status Scale (EDSS): 0-6

Exclusion Criteria:

* Diagnosed digestive pathology

Where it's running

  • Hasselt University
    Diepenbeek, Limburg, Belgium
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.