Clinical trial Recruiting at 1 site Interventional Ages 18 to 45

Flap versus flapless removal of a partially impacted lower wisdom tooth

Official title: Comparison of Postoperative Pain and Swelling in Flap Versus Flapless Technique for Surgical Removal of Partially Impacted Mandibular Third Molars: A Randomized Controlled Trial

Run by Watim Medical & Dental College · NCT07247929 · Data updated 2026-11-12

This trial will test whether a flapless technique causes less pain and swelling than the traditional flap method for adults (18–45) having a partially impacted lower wisdom tooth removed.

Quick facts

Study typeInterventional
Ages18 Years to 45 Years
SexAll
Enrollment160 (estimated)
SponsorWatim Medical & Dental College
Academic / other
Locations1 site (Islamabad, Islamabad)
StatusRecruiting
StartedAugust 15, 2024
Main results expectedFebruary 15, 2026
Study endsApril 15, 2026
Registry record updatedNovember 25, 2025
Trial IDNCT07247929 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–45 with a partially impacted mesioangular mandibular third molar, a second episode of pericoronitis, ipsilateral swelling, and no radiographic periodontal bone loss are ideal candidates.

Probably not a fit

Patients with diabetes, bleeding disorders, immunocompromised status, acute periapical infection or severe trismus, or fully impacted/other angulated molars are unlikely to benefit from or be eligible for this comparison.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial will assign 160 adults with partially impacted mesioangular mandibular third molars to either a flap or a flapless extraction technique. Pain will be recorded on a 10-point visual analogue scale and facial swelling will be measured with standardized anthropometric measurements, with primary comparison on the second postoperative day. All procedures will be performed by a single surgeon to minimize operator variability. The trial excludes patients with systemic conditions, bleeding disorders, acute infections, or severe trismus to reduce confounding factors.

Why it matters

Potential benefit: If successful, the flapless approach could reduce early postoperative pain and facial swelling, helping patients recover faster after lower wisdom tooth removal.

How similar studies have gone: Previous small trials and case series have suggested flapless extraction may reduce early pain and swelling in some patients, but results across studies are mixed and not definitive.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18-45 years

  * Either gender
  * Partially impacted mesioangular mandibular third molar confirmed clinically and radiographically
  * Second episode of pericoronitis
  * Swelling present on the affected side
  * No bone recession or periodontal disease on radiograph

Exclusion Criteria:

* HIV or HBV infection

  * Diabetes or other metabolic disorders
  * Bleeding disorders including von Willebrand disease, thalassemia, hemophilia, thrombocytosis, or thrombocytopenia
  * Periapical infection or acute pericoronitis at time of surgery
  * Severe trismus
  * Immunocompromised status

Where it's running

  • Watim Medical College&Dental Hospital
    Islamabad, Islamabad, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.