Finding the best lidocaine dose to reduce pain during propofol injection for anesthesia
Optimal Lidocaine Propofol Mixture for Painless Induction of Anesthesia
Sohag University · NCT05898061
This study is testing the best amount of lidocaine to mix with propofol to see if it can reduce pain during the injection for people having elective surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Sohag University (other) |
| Locations | 1 site (Sohag) |
| Trial ID | NCT05898061 on ClinicalTrials.gov |
What this trial studies
This research aims to identify the optimal dose of lidocaine mixed with propofol to minimize pain during the injection of propofol for general anesthesia. The study will utilize a modified Dixon's up-and-down method to assess pain severity in patients aged 18-60 years undergoing elective surgery. It will evaluate various outcomes, including pain scale during injection, heart rate changes, and patient satisfaction. The study will be conducted at Sohag University Hospital with a focus on ASA I and II patients, excluding those with certain medical conditions.
Who should consider this trial
Good fit: Ideal candidates are patients aged 18 to 60 years scheduled for elective surgery under general anesthesia with ASA physical status I or II.
Not a fit: Patients with a history of drug allergies, hepatic or renal impairment, cardiac issues, neurologic deficits, psychiatric disorders, or those requiring preoperative sedation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve the comfort of patients during anesthesia induction by reducing injection pain.
How similar studies have performed: Previous studies have explored lidocaine's effectiveness in reducing propofol injection pain, but this specific evaluation of optimal dosing is less commonly tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients scheduled for elective surgery under general anesthesia. * Aged 18 to 60 years * American Society of Anesthesiologists physical status I \& II Exclusion Criteria * History of drug allergy * Hepatic or renal impairment .Cardiac disease * Neurologic deficits ,psychiatric disorders * Anxious patients who need sedation preoperatively
Where this trial is running
Sohag
- Sohag University Hospital — Sohag, Egypt (RECRUITING)
Study contacts
- Study coordinator: Fawzy A Badawy, MD
- Email: fawzy_saleem@med.sohag.edu.eg
- Phone: 00201004862474
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pain, During Injection of Propofol for Induction of Anesthesia, Propofol - Lidocaine - Painless Induction