Fibrin clot structure and thrombin production after urogynecological surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project measures blood fibrin clot properties and thrombin generation in women after urogynecological surgery for uterine prolapse or urinary incontinence. Blood samples will be analyzed for clot permeability, susceptibility to fibrinolysis, and thrombin generation assays. Eligible participants are women aged 18–70 who undergo surgery after pharmacologic treatment failure, excluding those with congenital or acquired thrombophilia or prolonged thromboprophylaxis. No investigational treatments are given; clinical data and laboratory measurements will be correlated to characterize postoperative clotting phenotypes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18-70
* treatment failure (pharmacotherapy) due to uterine prolapse or urine incontinence

Exclusion Criteria:

* prolonged thromboprophylaxis
* planned surgery other than due to urine incontinence/uterine prolapse
* acquired or congenital thrombophilia

Where it's running

• Gynecological Endocrinology Department
  Krakow, Małopolska, Poland Recruiting

Study contacts

• Study coordinator: Magdalena MP Piróg, MD, PhD
• Email: magda.m.pulka@gmail.com
• Phone: +48 604514915

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.