Fiber-enriched soda before a high-fat meal to see how it affects cardiometabolic factors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Healthy adults aged 18–50 will participate in a crossover-like study where they receive a prebiotic soda or a control beverage before a high-fat meal, with two in-lab visits spaced about a week apart. Key measurements include anthropometrics, blood pressure, and cardiometabolic responses during each visit, along with activity tracking and dietary records beforehand. Prescreening and screening visits establish eligibility, and participants wear a fitness tracker and complete a short food log surrounding the study visits. The trial is sponsored by Ball State University and conducted at Ball State's Health Professions Building in Muncie, Indiana.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* You are 18-50 years old
* BMI is between 18.5-35.0 kg/m2 - this BMI requirement is due to our research aims.
* You are not pregnant or expecting to become pregnant (females only).
* You are not postmenopausal (females only).
* You have not been diagnosed with a cardiometabolic condition (e.g., cardiovascular disease, type 2 diabetes)
* You have not been diagnosed with a chronic inflammatory condition (e.g., rheumatoid arthritis, inflammatory bowel disease).
* You do not regularly take anti-inflammatory drugs (more than 2x week) or are able to temporarily suspend use of anti-inflammatory drugs.
* You do not use lipid-lowering drugs (e.g., statins), glucose-lowering drugs (e.g., metformin) tobacco products, or any illicit drugs.
* You do not have a pacemaker.
* You do not have dietary restrictions prohibiting you from eating the provided meal (e.g., food allergies/intolerance to beef or sweet potato).
* You have not used antibiotics or probiotics in the last month (probiotic containing foods like yogurt are allowed).
* You do not use weight-loss medications (e.g., Ozempic, Wegovy)
* You have not had any surgery that alters the stomach/gastrointestinal tract (e.g., gastric sleeve, gastric bypass).

Exclusion Criteria:

* You are not 18-50 years old.
* Your BMI is \<18.5 or \> 35.0 kg/m2 - this BMI requirement is due to our research aims
* You are pregnant or expecting to become pregnant (females only).
* You are postmenopausal (females only).
* You have been diagnosed with a cardiometabolic condition (e.g., cardiovascular disease, type 2 diabetes)
* You have been diagnosed with a chronic inflammatory condition (e.g., rheumatoid arthritis, inflammatory bowel disease).
* You regularly take anti-inflammatory drugs (more than 2x week) or are unable to temporarily suspend use of anti-inflammatory drugs.
* You use lipid-lowering drugs (e.g., statins), glucose-lowering drugs (e.g., metformin) tobacco products, or any illicit drugs
* You have a pacemaker.
* You do have dietary restrictions prohibiting you from eating the provided meal (e.g., food allergies/intolerance to beef or sweet potato).
* You have used antibiotics or probiotics in the last month.
* You use weight-loss medications (e.g., Ozempic, Wegovy).
* You have had a surgery that alters the stomach/gastrointestinal tract (e.g., gastric sleeve, gastric bypass).

Where it's running

• Health Professions Building, Ball State University
  Muncie, Indiana, United States Recruiting

Study contacts

• Principal investigator: Bryans Keirns, Principal Investigator — Ball State University
• Study coordinator: Bryant Keirns, Principal Investigator
• Email: bryant.keirns@bsu.edu
• Phone: 765-285-8356

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.