Fentanyl versus ketorolac added to peribulbar local anesthesia for anterior eye surgeries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults scheduled for anterior segment operations under peribulbar block are assigned to receive lidocaine/bupivacaine/hyaluronidase alone or with fentanyl or ketorolac as an adjuvant. The trial compares onset and quality of akinesia, duration of anesthesia, postoperative pain scores, and need for rescue analgesia while recording adverse effects. Fentanyl is an opioid adjuvant thought to improve akinesia and postoperative analgesia, whereas ketorolac is an NSAID that may reduce pain without opioid-related sedation or respiratory effects. Outcomes are collected during the operation and in the immediate postoperative period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age over 18 years old.
* Both sexes.
* American Society of Anesthesiologists (ASA) physical status I-III.
* Scheduled to undergo operations for anterior segment surgeries of the eye under local (peribulbar) anesthesia.

Exclusion Criteria:

* Patient's refusal.
* Known allergy or hypersensitivity to aspirin or nonsteroidal anti-inflammatory medications.
* Patients with contraindications to local anesthetics, such as high axial length or patients with high preoperative intraocular pressure.
* If cases develop severe pain intraoperatively from the start, necessitating rescue analgesia and sedation or requiring conversion to general anesthesia.
* Infection at the site of injection.
* Patients with coagulopathies or on anticoagulants.
* Impaired renal function.

Where it's running

• Cairo University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Aya M Abo Zied, Master
• Email: Ayamezoo111@gmail.com
• Phone: 00201126720605

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.