Feasibility of comparing imaging strategies for acute stroke

• Code Stroke Imaging (CSI): MRI Or CT As First Scan For Acute Stroke Evaluation And Management

University of Texas at Austin · NCT06270927

This study is testing different imaging methods for people who might have an acute stroke to see which one works best for their treatment.

Quick facts

Study typeObservational
Enrollment600 (estimated)
Ages18 Years to 120 Years
SexAll
SponsorUniversity of Texas at Austin (other)
Locations1 site (Austin, Texas)
Trial IDNCT06270927 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the feasibility of a comparative effectiveness framework for imaging strategies in patients with suspected acute ischemic stroke. It involves a prospective cohort of patients presenting to the Emergency Department, where the clinical stroke team will utilize standard imaging modalities while maintaining blinding for data analysis. All patients will receive standard-of-care therapy based on established clinical guidelines, and the analysis will be conducted on an 'intent-to-scan' basis, including all qualifying patients in their assigned imaging cohort.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who present with symptoms suggestive of stroke within 24 hours of their last known well time.

Not a fit: Patients who are transferred from other facilities or have contraindications for brain perfusion scans may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the effectiveness of imaging strategies in acute stroke management, potentially leading to better patient outcomes.

How similar studies have performed: While this approach is novel in its specific framework, similar studies have shown promise in improving stroke imaging strategies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Time last known well to presentation ≤ 24 hours
* Code-stroke (suspected treatable ischemic stroke) called prior to or upon arrival to Emergency Department
* Presenting to Emergency Department for first time during study period

Exclusion Criteria:

* Transfer patients
* Contraindication for brain perfusion scan
* Prior inclusion in study

Where this trial is running

Austin, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Brain Ischemia, Stroke, Neuroimaging

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.