Fast Breast MRI for Black Women with Dense Breasts
Supplemental Screening for Breast Cancer With Abbreviated Breast MR for Black Women With Increased Breast Density
This study is testing a quick breast MRI to see if it can improve cancer screening for African American women with dense breasts.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 40 Years to 75 Years |
| Sex | Female |
| Sponsor | Abramson Cancer Center at Penn Medicine Academic / other |
| Locations | 1 site (Philadelphia, Pennsylvania) |
| Trial ID | NCT04854304 on ClinicalTrials.gov |
What this trial studies
This study aims to recruit 500 African American women with heterogeneously and extremely dense breasts to undergo a fast breast MRI examination. Participants must have had a negative digital breast tomosynthesis (DBT) examination within the past 11 months and be clinically asymptomatic. The recruitment will utilize the EPIC database to identify eligible candidates based on their last mammogram date, and interested women can contact research coordinators for participation. The study seeks to enhance breast cancer screening methods specifically for this demographic.
Who should consider this trial
Good fit: Ideal candidates are African American women with dense breast tissue who have had a recent negative mammogram and are asymptomatic.
Not a fit: Patients who are pregnant, symptomatic for breast disease, or have not had a mammogram in the past 11 months may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve early detection of breast cancer in Black women with dense breasts, leading to better outcomes.
How similar studies have performed: Other studies have shown promise in using MRI for breast cancer screening, particularly in women with dense breast tissue, indicating a potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. African American female 2. Negative DBT examination within eleven months prior to recruitment 3. Heterogeneoulsy and Extremely breast densities 4. Clinically asymptomatic- no palpable masses or focal thickening, etc. Exclusion Criteria: 1. Patients who are pregnant and lactating 2. Patient who have not had a mammogram (DBT) in the past 11months 3. Patients who are unwilling or unable to provide written informed consent 4. Patients symptomatic for breast disease (e.g. experiencing discharge, lumps, ect.) 5. Recent breast surgery in the past 2 years including breast enhancements (e.g. implants or injections) 6. Patients who are unable to received an MRI with Gadolinium contrast 7. Patients who have not had an MRI of the breast with the past year
Where this trial is running
Philadelphia, Pennsylvania
- Upenn — Philadelphia, Pennsylvania, United States (Recruiting)
Study contacts
- Principal investigator: Emily F Conant, MD — University of Pennsylvania
- Study coordinator: Jessica Nunez
- Email: Jessica.Nunez@pennmedicine.upenn.edu
- Phone: 215-746-6788
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.