Family-centered lifestyle program for Black prostate cancer survivors and their caregivers

Together Stronger: A Family-centered Lifestyle Intervention for Black Prostate Cancer Survivors and Their Caregivers

This trial tests whether a family-centered lifestyle program helps Black prostate cancer survivors and their caregivers increase physical activity and improve diet, physical functioning, quality of life, and family health climate compared with survivor-only and control groups.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 648 (estimated)
• Ages: 18 Years and up
• Sex: Male
• Sponsor: M.D. Anderson Cancer Center (Academic / other)
• Drugs / interventions: chemotherapy, immunotherapy, radiation
• Locations: 1 site (Houston, Texas)
• Trial ID: NCT07164456 on ClinicalTrials.gov

What this trial studies

The trial enrolls Black or African American adult prostate cancer survivors (stage 0–III) who have completed treatment and a family caregiver willing to participate. Participants are assigned to a family-centered intervention, a survivor-only intervention, or a control group and receive education sessions and questionnaires to support lifestyle change. Primary outcomes are changes in moderate-to-vigorous physical activity (MVPA) and overall diet quality measured at post-intervention, with secondary outcomes including 6-minute walk test (6MWT), quality of life, and family health climate assessed at post-intervention and 6 months. The study also examines mediators and moderators of the intervention to understand who benefits and why.

Who should consider this trial

Good fit: Ideal candidates are Black or African American adults with stage 0–III prostate cancer who have completed treatment, can safely engage in physical activity, and have a family caregiver willing to join the program.

Not a fit: People with metastatic disease or other recent cancers, those receiving active cancer treatments, those already meeting physical activity guidelines, or those without an available caregiver are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, the program could help survivors and their caregivers increase exercise and improve diet, which may boost physical functioning, quality of life, and family support for healthy behaviors.

How similar studies have performed: Previous caregiver- and family-involved lifestyle programs in cancer survivors have shown improvements in activity, diet, and quality of life, though evidence specifically focused on Black prostate cancer survivor–caregiver pairs is limited.

Eligibility criteria

Eligibility Criteria

Survivors are eligible if they

* Are adults (≥18 years old)
* Self-identify as Black or African American;
* Were diagnosed with stage 0-III PCa; completed PCa treatment; (5) are able to be physically active, as determined by responses to the Physical Activity Readiness Questionnaire (PAR-Q); and
* Have a family caregiver willing to participate together. Individuals under active surveillance for PCa will be included.

Caregivers are eligible if they:

* Are adults (≥18 years old)
* Are able to be physically active, as determined by responses to the

Exclusion Criteria

Survivors are excluded if they:

* Have a prior history of other cancer or have metastatic cancer.
* Have planned concomitant immunotherapy, hormonal therapy, chemotherapy, or radiation therapy during the study period.
* Meet physical activity recommendations (i.e., 150 min of moderate intensity physical activity per week); and (4) are currently participating in a lifestyle or weight management program.

Caregivers are excluded if they:

* Have serious medical conditions (e.g., cancer, congestive heart failure, stroke, and dementia)
* Are currently participating in a lifestyle or weight management program.

Where this trial is running

Houston, Texas

• MD Anderson Cancer Center — Houston, Texas, United States (Recruiting)

Study contacts

• Principal investigator: Dalnim Cho, MD — MD Andersson Cancer Center
• Study coordinator: Dalnim Cho, MD

Conditions Family Centered; Black Ethnicity; Prostate Cancer Survivors