Factors that predict needing rescue ventilation during airway surgery with THRIVE
Determinants of Rescue Ventilation Requirement in Airway Surgery Under General Anesthesia With Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE): A Prospective Observational Study
We will test which factors predict needing rescue ventilation in adults having elective airway surgery under general anesthesia with THRIVE.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Seoul National University Hospital Academic / other |
| Locations | 1 site (Seoul) |
| Trial ID | NCT06925282 on ClinicalTrials.gov |
What this trial studies
This observational study will record oxygen saturation continuously during elective airway surgeries performed under general anesthesia with Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE). Investigators will note the time point when oxygen saturation falls below 92% and rescue ventilation is initiated. Clinical, anatomical, and anesthesia-related variables (for example age, severity of subglottic stenosis, anesthesia technique, and apnea duration) will be collected to identify predictors of rescue ventilation. Data will be analyzed to determine which factors are associated with desaturation events requiring intervention.
Who should consider this trial
Good fit: Adults undergoing elective airway surgery for subglottic stenosis under general anesthesia with THRIVE who can provide written informed consent.
Not a fit: Patients who are pediatric, undergoing emergency airway procedures, not managed with THRIVE, or who decline participation are unlikely to benefit from this study's findings.
Why it matters
Potential benefit: If successful, the findings could help clinicians predict and prevent oxygen desaturation, reducing emergency ventilations and improving safety during airway surgeries with THRIVE.
How similar studies have performed: THRIVE has been shown to prolong safe apnea and reduce desaturation in airway procedures, but using patient- and procedure-level predictors to forecast rescue ventilation events is relatively untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients undergoing elective airway surgery under general anesthesia with Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) * Patients who provide written informed consent Exclusion Criteria: * Patients who decline to participate in the study
Where this trial is running
Seoul
- Seoul National University Hospital — Seoul, South Korea (Recruiting)
Study contacts
- Study coordinator: Kyung Won Shin
- Email: skwskw126@gmail.com
- Phone: 02-2072-2469
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.