Factors that predict needing rescue ventilation during airway surgery with THRIVE
Official title: Determinants of Rescue Ventilation Requirement in Airway Surgery Under General Anesthesia With Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE): A Prospective Observational Study
Run by Seoul National University Hospital · NCT06925282 · Data updated 2026-11-12
We will test which factors predict needing rescue ventilation in adults having elective airway surgery under general anesthesia with THRIVE.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Seoul National University Hospital Academic / other |
| Locations | 1 site (Seoul) |
| Status | Recruiting |
| Started | April 25, 2025 |
| Main results expected | March 2027 |
| Study ends | April 2028 |
| Registry record updated | April 24, 2026 |
| Trial ID | NCT06925282 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults undergoing elective airway surgery for subglottic stenosis under general anesthesia with THRIVE who can provide written informed consent.
✕Probably not a fit
Patients who are pediatric, undergoing emergency airway procedures, not managed with THRIVE, or who decline participation are unlikely to benefit from this study's findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study will record oxygen saturation continuously during elective airway surgeries performed under general anesthesia with Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE). Investigators will note the time point when oxygen saturation falls below 92% and rescue ventilation is initiated. Clinical, anatomical, and anesthesia-related variables (for example age, severity of subglottic stenosis, anesthesia technique, and apnea duration) will be collected to identify predictors of rescue ventilation. Data will be analyzed to determine which factors are associated with desaturation events requiring intervention.
Why it matters
Potential benefit: If successful, the findings could help clinicians predict and prevent oxygen desaturation, reducing emergency ventilations and improving safety during airway surgeries with THRIVE.
How similar studies have gone: THRIVE has been shown to prolong safe apnea and reduce desaturation in airway procedures, but using patient- and procedure-level predictors to forecast rescue ventilation events is relatively untested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients undergoing elective airway surgery under general anesthesia with Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) * Patients who provide written informed consent Exclusion Criteria: * Patients who decline to participate in the study
Where it's running
-
Seoul National University Hospital
Seoul, South Korea Recruiting
Study contacts
- Study coordinator: Kyung Won Shin
- Email: skwskw126@gmail.com
- Phone: 02-2072-2469
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.