Clinical trial Recruiting at 1 site Interventional Ages 25 to 50 Women only

Facilitated positional release versus manual myofascial release for women with piriformis syndrome

Official title: Effects of Facilitated Positional Release Technique( FPRT) Vs Manual Myofascial Release Technique in Female Patients With Piriformis Syndrome.

Run by Foundation University Islamabad · NCT07044869 · Data updated 2026-11-12

This trial will test whether facilitated positional release or manual myofascial release better reduces pain and improves hip movement in women aged 25–50 with piriformis syndrome.

More Piriformis Syndrome trials

Quick facts

Study typeInterventional
Ages25 Years to 50 Years
SexWomen only
Enrollment38 (estimated)
SponsorFoundation University Islamabad
Academic / other
Locations1 site (Islamabad)
StatusRecruiting
StartedJuly 26, 2024
Main results expectedAugust 20, 2025
Study endsAugust 20, 2025
Registry record updatedJuly 1, 2025
Trial IDNCT07044869 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are women aged 25–50 diagnosed with piriformis syndrome who have had pain for at least two months and no major lumbar or hip surgery or radiculopathy.

Probably not a fit

Patients with lumbar radiculopathy, hip osteoarthritis, prior total hip replacement, or recent lumbar fracture/trauma are excluded and are unlikely to benefit from the study treatments.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized controlled trial at Foundation University College of Physical Therapy in Islamabad comparing two hands-on therapies for piriformis syndrome in women. Participants are randomized to receive either facilitated positional release technique (FPRT) or manual myofascial release technique delivered over two weeks. Baseline and follow-up measurements include hip range of motion (abduction, adduction, internal and external rotation), the Numeric Pain Rating Scale (NPRS), and the Lower Extremity Functional Scale (LEFS). The trial excludes patients with lumbar radiculopathy, prior lumbar or hip surgery, recent lumbar fracture/trauma, or hip osteoarthritis.

Why it matters

Potential benefit: If successful, the trial could identify a more effective manual therapy to lower pain and restore hip motion and function in women with piriformis syndrome.

How similar studies have gone: Previous small trials and clinical reports show some benefit of manual myofascial techniques for related buttock and hip pain, while the evidence for facilitated positional release specifically is more limited but promising.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • 25-50 years Only females Diagnosed piriformis syndrome Pain from 2 months

Exclusion Criteria:

* Lumbar Radiculopathy Fracture trauma to lumbar spine surgery/ total hip replacement hip OA

Where it's running

  • Foundation University College of Physical Therapy
    Islamabad, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.