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Extended blood clot prevention after abdominal or pelvic cancer surgery

Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network (STOP-VTE)

Observational Wake Forest University Health Sciences · NCT07215624

See how surgeons and surgical advanced practice providers in the NCORP network use extended blood clot prevention after abdominopelvic cancer surgery.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years and up
SexAll
SponsorWake Forest University Health Sciences Academic / other
Locations59 sites (Fort Smith, Arkansas and 58 other locations)
Trial IDNCT07215624 on ClinicalTrials.gov

What this trial studies

This observational project surveys surgeons and surgical advanced practice providers within the National Cancer Institute Community Oncology Research Program (NCORP) about their use of guideline-recommended extended venous thromboembolism (VTE) prophylaxis following abdominopelvic cancer surgery. A subset of respondents will be invited to semi-structured interviews to identify barriers and facilitators to prescribing and to gauge acceptability of clinical decision support tools. Selected sites will attempt electronic health record queries to identify patients undergoing cancer surgery and to detect prescriptions for guideline-concordant extended prophylaxis. The combined approach maps current practice patterns and tests the feasibility of EHR-based identification across community oncology sites.

Who should consider this trial

Good fit: Ideal participants are surgeons and surgical advanced practice providers who perform or manage postoperative care for gastrointestinal, genitourinary, or gynecologic cancer surgeries at NCORP-affiliated sites.

Not a fit: Patients not undergoing abdominopelvic cancer surgery or those treated outside NCORP-affiliated hospitals are unlikely to receive direct benefit from this project.

Why it matters

Potential benefit: If successful, this could increase use of guideline-recommended extended VTE prophylaxis after cancer surgery and reduce postoperative blood clots and their complications.

How similar studies have performed: Randomized trials have shown that extended VTE prophylaxis can reduce postoperative thromboembolism after abdominal cancer surgery, but implementation and adherence studies in community oncology networks like NCORP are limited.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

SURGEON ELIGIBILITY CRITERIA FOR OPEN STEP 0 ENROLLMENT:

\* Any surgeon performing gastrointestinal, genitourinary, or gynecologic cancer surgery within an NCORP site, including general surgeons, surgical specialists, urologists, and gynecologists. Surgeons do not need to be involved in research or have a Cancer Therapy Evaluation Program Identification (CTEP ID) to participate in this study

SURGICAL APP ELIGIBILITY CRITERIA FOR OPEN STEP 0 ENROLLMENT:

\* APPs providing postoperative care to patients operated by surgeons performing gastrointestinal, genitourinary, or gynecologic cancer surgery within an NCORP site, including general surgeons, surgical specialists, urologists, and gynecologists. Surgical APPs do not need to be involved in research or have a CTEP ID to participate in this study

SURGEON ELIGIBILITY CRITERIA FOR OPEN STEP 1 ENROLLMENT:

\* Must have completed the STOP-VTE Survey - Surgeon electronically (preferred) or on paper and have it transferred to Research Electronic Data Capture (REDCap) by the contact person(s)

SURGICAL APP ELIGIBILITY CRITERIA FOR OPEN STEP 1 ENROLLMENT:

\* Must have completed the STOP-VTE Survey - APP electronically (preferred) or on paper and have it transferred to REDCap by the contact person(s)

SITE ELIGIBILITY PART 1-SITE ENROLLMENT IN OPEN:

\* Have at least one eligible surgeon or surgical APP who completed the STOP-VTE Survey - Surgeon/APP

Exclusion Criteria:

* N/A

Where this trial is running

Fort Smith, Arkansas and 58 other locations

+9 more sites — see ClinicalTrials.gov for the full list.

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.