Exploring ultrasound signs in knee septic arthritis
Exploratory Study of Ultrasound Signs of Native Septic Arthritis of the Knee
Poitiers University Hospital · NCT04952220
This study looks at how ultrasound images change over time in people with knee septic arthritis to see if these changes can help predict their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Poitiers University Hospital (other) |
| Locations | 7 sites (Nantes, Pays De La Loire and 6 other locations) |
| Trial ID | NCT04952220 on ClinicalTrials.gov |
What this trial studies
This observational study aims to describe ultrasound abnormalities in patients with bacteriologically proven native septic arthritis of the knee at multiple time points: Day 0, Day 10, 6 weeks, 3 months, and 6 months. It will also investigate potential poor prognostic factors and associations between initial ultrasound findings and clinical outcomes, including the use of joint lavage. The study will involve regular ultrasound assessments to monitor changes and correlations with clinical and biological factors throughout the treatment period.
Who should consider this trial
Good fit: Ideal candidates include adults with bacteriologically confirmed native septic arthritis of the knee.
Not a fit: Patients with joint material present or those with tuberculosis-related arthritis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the understanding and management of septic arthritis in the knee, leading to better patient outcomes.
How similar studies have performed: While there may be studies on ultrasound in arthritis, this specific focus on native septic arthritis is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female of legal age * Bacteriologically proven native septic arthritis * Meets the definition of septic arthritis: Bacteriological documentation of joint puncture fluid-Native articulation * Free subject, without guardianship or trusteeship, or subordination * Non-opposition of the patient after clear and fair information about the study Exclusion Criteria: * Presence of material in the affected joint * Arthritis with Mycobacterium Tuberculosis. * Patients benefiting from a reinforced protection, namely: minors, pregnant and/or breast-feeding women, persons deprived of liberty by a judicial or administrative decision, adults under legal protection
Where this trial is running
Nantes, Pays De La Loire and 6 other locations
- CHU de Nantes — Nantes, Pays De La Loire, France (RECRUITING)
- CH D'Angouleme — Angoulême, France (NOT_YET_RECRUITING)
- CH de La roche-sur-yon — La Roche-sur-Yon, France (RECRUITING)
- CH De La Rochelle — La Rochelle, France (RECRUITING)
- CH de Niort — Niort, France (RECRUITING)
- CHU de Poitiers — Poitiers, France (RECRUITING)
- CHU de Rennes — Rennes, France (RECRUITING)
Study contacts
- Principal investigator: GERVAIS Elisabeth — Poitiers University Hospital
- Study coordinator: GERVAIS Elisabeth
- Email: elisabeth.gervais@chu-poitiers.fr
- Phone: 05 49 44 44 65
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Ultrasound Therapy, Complications, Septic Arthritis, Knee Arthritis