Exploring TIVDAK for Women with Recurrent Cervical Cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of TIVDAK, a treatment for cervical cancer that has returned after chemotherapy. Participants will receive TIVDAK infusions every three weeks and undergo eye assessments at various stages throughout the treatment. The primary goal is to evaluate potential side effects, particularly those related to the eyes, in women with recurrent or metastatic cervical cancer. Participants must not have any active eye issues and must be willing to undergo the required ocular tests.

Why it matters

Who can join: the full rules

Inclusion criteria:

1. Must have recurrent or metastatic cervical cancer with disease progression on or after chemotherapy
2. Treating physician has determined that treatment with Tivdak is appropriate for the participant according to US Prescribing Information
3. Must sign an informed consent form indicating that the participant understands the purpose and procedures required for the study and are willing to participate
4. Must be willing to undergo repeated ocular assessments as required by the study and regular clinic visits according to local standard practice of the study site
5. Must agree to use effective contraception according to the US Prescribing Information

Exclusion criteria:

1. Active ocular disease at baseline per investigator assessment
2. Previous treatment with Tivdak
3. Previous administration of an investigational drug within 30 days
4. Any medical or psychiatric condition including recent (within the past year) or active suicidal ideation/behavior or laboratory abnormality that may, in the investigator'

Where it's running

• HonorHealth Cancer Care - Biltmore - AZCCC Imaging
  Phoenix, Arizona, United States Recruiting
• HonorHealth Cancer Care - Biltmore - HonorHealth Research Pharmacy
  Phoenix, Arizona, United States Recruiting
• HonorHealth Research Institute (Arizona Center for Cancer Care) - HonorHealth Cancer Care -Biltmore
  Phoenix, Arizona, United States Recruiting
• Sonora Quest Laboratories, LLC
  Phoenix, Arizona, United States Recruiting
• South West Medical Imaging (SMIL)
  Phoenix, Arizona, United States Recruiting
• Schwartz Laser Eye Center
  Scottsdale, Arizona, United States Recruiting

+85 more sites. See ClinicalTrials.gov for the full list.

Study contacts

• Study coordinator: Pfizer CT.gov Call Center
• Email: ClinicalTrials.gov_Inquiries@pfizer.com
• Phone: 1-800-718-1021

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.