Exploring the psychological effects of GTN treatment on women
Official title: The Psychological Impact of GTN on Women Who Have Completed Chemotherapy Treatment
Run by Sheffield Teaching Hospitals NHS Foundation Trust · NCT06169644 · Data updated 2026-11-12
This study is trying to understand how women feel emotionally after finishing treatment for Gestational Trophoblastic Neoplasia and what kind of support they have received.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 16 Years to 55 Years |
| Sex | Women only |
| Enrollment | 20 (estimated) |
| Sponsor | Sheffield Teaching Hospitals NHS Foundation Trust Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Sheffield, South Yorkshire) |
| Status | Recruiting |
| Started | May 15, 2024 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | February 21, 2025 |
| Trial ID | NCT06169644 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women who have been treated with chemotherapy for GTN and completed their treatment between 6 weeks and 24 months ago.
✕Probably not a fit
Patients who received treatment less than 6 weeks ago or more than 24 months ago, as well as non-English speakers, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to understand the psychological impact of Gestational Trophoblastic Neoplasia (GTN) on women who have completed chemotherapy treatment. It involves conducting semi-structured telephone interviews with a sample of 20 women, who are between 6 weeks and 24 months post-treatment. The study seeks to gain insights into their emotional experiences, assess the adequacy of psychological support provided by health professionals, and identify sources of support accessed by patients after treatment. Thematic analysis will be employed to analyze the interview data and provide a comprehensive understanding of the patients' experiences.
Why it matters
Potential benefit: If successful, this study could enhance psychological support for women recovering from GTN, leading to improved mental health outcomes.
How similar studies have gone: While there is limited research specifically on the psychological impact of GTN, similar studies on cancer survivors have shown the importance of addressing psychological support needs.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Treated with chemotherapy for a GTN diagnosis * Completed treatment between 6 weeks and 24 months * Are able to provide informed consent * Have no cognitive impairment as judged by the treating clinician Exclusion Criteria: * Treatment received less than 6 weeks ago * Treatment received more than 24 months ago * Non-English speaking
Where it's running
-
Weston Park Hospital
Sheffield, South Yorkshire, United Kingdom Recruiting
Study contacts
- Principal investigator: Kamaljit Singh — Nurse Consultant
- Study coordinator: Kamaljit Singh
- Email: kamaljitsingh@nhs.net
- Phone: 01142265274
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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A cohort study for patients with Gestational Trophoblastic Neoplasia
This study is gathering information from patients with Gestational Trophoblastic Neoplasia to better understand their treatment and outcomes, including fertility and recurrence rates.
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Combination treatment of toripalimab and actinomycin-D for gestational trophoblastic neoplasia
This study is testing if combining two drugs, toripalimab and actinomycin-D, can help people with gestational trophoblastic neoplasia respond better than just using actinomycin-D alone.
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This study is testing if a new combination of toripalimab and actinomycin-D can effectively treat gestational trophoblastic neoplasia in patients with a specific score, to see if it works better than standard chemotherapy.
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Camrelizumab plus apatinib for high‑risk gestational trophoblastic neoplasia
This trial will test whether adding camrelizumab and apatinib to chemotherapy helps women with ultra high‑risk or chemo‑refractory/relapsed high‑risk gestational trophoblastic neoplasia achieve remission.
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Hysteroscopic Repeat Curettage as First-Line Treatment for Low-Risk Postmolar GTN
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.