Exploring the mechanisms behind eating disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the underlying mechanisms of eating disorders, specifically anorexia nervosa and bulimia nervosa. By utilizing a combination of clinical data, neuroimaging techniques such as functional and structural MRI, electroencephalogram (EEG) readings, and inflammatory cytokine analysis, the study seeks to identify biomarkers that could aid in diagnosis and treatment effectiveness. The research focuses on understanding the neuro-mechanisms that contribute to the etiology and maintenance of these disorders.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Anorexia nervosa

1. Anorexia nervosa according to Diagnostic and Statistical Manual of Mental Disorders (5th edition) (DSM-5);
2. Age: 13-35 (including 13 and 35)
3. BMI: 13-17.5kg/m\^2
4. The participants and/or their legal guardians ( for participants who are younger than 18-year-old) sign the informed consent form voluntarily and agree to participate in all visits and examinations as required by the trial protocol.
5. Do not take any psychiatric medications in past one month.

Bulimia nervosa

1. Bulimia nervosa according to Diagnostic and Statistical Manual of Mental Disorders (5th edition) (DSM-5);
2. Age: 13-35 years old (including 13 and 35)
3. The participants and/or their legal guardians ( for participants who are younger than 18-year-old) sign the informed consent form voluntarily and agree to participate in all visits and examinations as required by the trial protocol.
4. Do not take any psychiatric medications in past one month.

Exclusion Criteria:

1. Patients who meet DSM-5 diagnostic criteria for other mental disorders: Major depressive disorder, anxiety, obsessive-compulsive disorder, personality disorder, mental retardation; drug and/or alcohol dependence;
2. Patients who receive repetitive Transcranial Magnetic Stimulation (rTMS) or modified electroconvulsive therapy (MECT) treatment in past six months.
3. Patients with severe suicidal tendencies or suicidal behavior
4. Pregnant or lactating women;
5. Patients with MRI contraindications;
6. Patients who are regarded as unsuitable by investigators for this clinical trial.

Where it's running

• Institute of Mental Health, Peking University Sixth Hospital
  Beijing, China Recruiting

Study contacts

• Study coordinator: Tian-Mei Si, Ph.D
• Email: sitianmei@bjmu.edu.cn
• Phone: 861062723748

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Gastrointestinal symptoms during weight restoration in anorexia nervosa and bulimia nervosa with different diets

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• Using fMRI to study brain activity in patients with eating disorders

  This study is testing how brain activity changes in people with anorexia or bulimia over a year to see if these changes relate to their symptoms getting better.

  Recruiting at 2 sites Meyer Children's Hospital IRCCS · Florence and 1 other locations · NCT06874348

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.