Exploring the links between sleep, eating patterns, gut health, and obesity
Interaction of Sleep, Diurnal Eating Pattern, Gut Microbiota, and Obesity
This study is testing a new mobile app to see if improving sleep and eating habits can help people with obesity feel better and manage their weight.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Turku University Hospital Government |
| Locations | 1 site (Turku) |
| Trial ID | NCT04850391 on ClinicalTrials.gov |
What this trial studies
This study aims to investigate the relationships between subjective sleep quality, diurnal eating patterns, gut microbiota, and obesity. It will develop and test a cost-effective mobile app designed to promote lifestyle changes through an E-health approach. Participants will be assessed for differences in sleep quality, eating patterns, and gut microbiome at baseline, and changes will be monitored following the intervention across different work schedules. The study seeks to provide a multifactorial understanding of obesity and weight regulation.
Who should consider this trial
Good fit: Ideal candidates for this study are community-dwelling adults aged 18 to 65 with a BMI between 18.5 and 30 kg/m2 or those with a BMI greater than 30 kg/m2, including patients with obstructive sleep apnea using CPAP.
Not a fit: Patients currently undergoing antimicrobial treatment or those with inflammatory bowel diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to effective lifestyle interventions that help individuals manage obesity through improved sleep and eating habits.
How similar studies have performed: While there is emerging evidence on the individual factors of sleep, eating patterns, and gut microbiota in obesity, this study's comprehensive approach is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Community dwelling 18 - 65 year old adults * BMI 18.5 - 30 kg/m2 (n = 40, M:F = 1:1) * BMI \> 30 kg/m2 (n = 40, M:F = 1:1) * OSAS patients with BMI \> 30 kg/m2 using nasal continuous positive airway pressure (CPAP) treatment on an average \> 4 h/d (n = 40, M:F = 1:1). Exclusion Criteria: * Antimicrobial treatment within 3 months prior the baseline visit * Inflammatory bowel diseases
Where this trial is running
Turku
- Turku University Hospital — Turku, Finland (Recruiting)
Study contacts
- Principal investigator: Tarja Saaresranta, MD, PhD — Turku University Hospital
- Study coordinator: Tarja Saaresranta, MD, PhD
- Email: tasaare@utu.fi
- Phone: +35823130000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.