Exploring the link between ultra-processed foods and eosinophilic esophagitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the potential role of compounds derived from ultra-processed foods in the development of eosinophilic esophagitis (EoE), a chronic inflammatory condition of the esophagus. It aims to evaluate dietary habits and their correlation with EoE symptoms in children and adolescents aged 3 to 18 years. Participants will include diagnosed EoE patients and age- and sex-matched healthy controls, with a focus on understanding how diet may influence the pathogenesis of this condition. The study will involve dietary evaluations to gather relevant data.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* both sexes
* age between 3-65 years
* sure diagnosis of eosinophilic esophagitis
* age- and sex-matched healthy controls
* parents/tutor written informed consent.

Exclusion Criteria:

* lack of written informed consent;
* non-Caucasian ethnicity
* age at enrollment \< 3 or \>65 years
* simultaneous presence of other chronic diseases: eosinophilic gastroenteritis, eosinophilic colitis, achalasia, GERD, hypereosinophilia syndrome, IBD, fungal or viral infections, connective tissue disorders, autoimmune diseases, vasculitis, bullous dermatosis with oesophageal involvement (pemphigus), drug hypersensitivity reactions, drug-induced oesophagitis, graft vs host disease, monogenic disorders (Marfan syndrome type 2, HIES, PTEN).
* presence of tattoos, scars, moles or particular lesions on both forearms

Where it's running

• Department of Traslational Medical Science - University of Naples Federico II
  Naples, Naples, Italy Recruiting
• Department of Traslational Medical Science - University of Naples Federico II
  Naples, Naples, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.