Exploring the link between sleep spindles and social memory in children with autism
The Involvement of Sleep Spindle Waves in the Auxiliary Diagnosis of Social Memory Disorders in Children With Autism Spectrum Disorders
First Affiliated Hospital Xi'an Jiaotong University · NCT06306378
This study is trying to see if there's a connection between sleep patterns and how well children with autism remember faces and cars compared to kids without autism.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 6 Years to 18 Years |
| Sex | All |
| Sponsor | First Affiliated Hospital Xi'an Jiaotong University (other) |
| Locations | 1 site (Xi'an, Shaanxi) |
| Trial ID | NCT06306378 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between sleep spindles and social memory deficits in children diagnosed with autism spectrum disorder (ASD). It aims to recruit 30 children with ASD and 30 typically developing children to participate in face and car recognition memory tests. Following these tests, nighttime EEG recordings will be conducted to analyze sleep spindle activity. The study will utilize machine learning models to assess the correlation between social memory levels and spindle activity, potentially providing insights for auxiliary diagnosis of social memory disorders in children with ASD.
Who should consider this trial
Good fit: Ideal candidates for this study are children aged 6-18 diagnosed with autism spectrum disorder and with an IQ score of 75 or higher.
Not a fit: Patients with additional mental illnesses, sleep disorders, or atypical EEG patterns may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic tools for social memory disorders in children with autism.
How similar studies have performed: While the relationship between sleep spindles and memory has been studied, this specific correlation in children with autism is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children with ASD diagnosed through DSM-V (Healthy controls do not have this requirement) * IQ score ≥ 75（WISC-IV，Wechsler Intelligence Scale for Children） * Age: 6-18 * Not receiving psychotropic medication (Or stopping medication for at least 2 weeks before the experiment) Exclusion Criteria: * In addition to ASD, other mental illnesses are also combined * Presence of a sleep disorder, sleep apnea, periodic leg movements during sleep, or atypical EEG patterns * Left handed
Where this trial is running
Xi'an, Shaanxi
- First Afflicated Hospital Xian Jiaotong University — Xi'an, Shaanxi, China (RECRUITING)
Study contacts
- Study coordinator: Dongqi Cui, PhD
- Email: 18501059233@163.com
- Phone: 18501059233
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Autism Spectrum Disorder, Sleep spindles, Social Memory Deficits, Diagnosis