Exploring the link between phenol exposure and pregnancy outcomes after embryo transfer
Relationship Between Exposure to Phenols and Pregnancy Outcomes After Embryo Transfer
Tongji Hospital · NCT06767202
This study is trying to see if being exposed to phenols affects pregnancy outcomes for women who are having embryo transfers during fertility treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1200 (estimated) |
| Ages | 20 Years and up |
| Sex | Female |
| Sponsor | Tongji Hospital (other) |
| Locations | 1 site (WuHan, Hubei) |
| Trial ID | NCT06767202 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between exposure to phenols and pregnancy outcomes in women undergoing embryo transfer as part of assisted reproductive technology. It utilizes paper questionnaires to gather general health information, dietary assessments, and medical records related to assisted reproduction protocols and pregnancy outcomes. Additionally, urine samples will be analyzed using high-performance liquid chromatography mass spectrometry to measure phenol levels. The study aims to determine if phenol exposure is associated with adverse pregnancy outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are Chinese women over the age of 20 who are undergoing IVF or ICSI treatments and have complete clinical and questionnaire data.
Not a fit: Patients who are receiving sperm or egg donation treatments or have serious health conditions that contraindicate pregnancy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into how phenol exposure affects pregnancy outcomes, potentially guiding dietary recommendations for women undergoing assisted reproductive technology.
How similar studies have performed: While the specific relationship between phenols and pregnancy outcomes is not extensively studied, similar observational studies have shown associations between environmental exposures and reproductive health outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Chinese citizens over the age of 20; 2. IVF/ICSI assisted reproductive treatment in our center; 3. Complete clinical data, reproductive outcomes and questionnaire data of both sexes; 4. Knowing about this research and voluntarily accepting this research; Exclusion Criteria: 1. The patient receives sperm or egg donation treatment; 2. The patient gave up the egg collection operation due to various reasons, and the cycle was canceled; 3. The patient abandons treatment before achieving clinical pregnancy, but the fertile frozen embryo is not transferred; 4. There are contraindications to pregnancy, such as serious liver and kidney diseases, malignant tumors, serious mental diseases, uncorrected coagulation function abnormalities or endocrine indicators abnormalities; 5. Incomplete or missing clinical data or follow-up data;
Where this trial is running
WuHan, Hubei
- Reproductive center，tongji hospital，huazhong university of science and technology — WuHan, Hubei, China (RECRUITING)
Study contacts
- Study coordinator: Liu keqin
- Email: liukeqin0208@163.com
- Phone: 0086-18089654832
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Embryo Transfer, Dietary polyphenols, bisphenols