Exploring the impact of nasal breathing on physical capacity

The Role of the Nose for Physical Capacity

PHASE4 · Sorlandet Hospital HF · NCT04712799

This study is testing if using a nasal decongestant can help people with nasal blockage and COPD, as well as healthy individuals and athletes, breathe better and improve their physical performance.

Quick facts

PhasePHASE4
Study typeInterventional
Enrollment67 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorSorlandet Hospital HF (other gov)
Locations1 site (Kristiansand, Agder)
Trial IDNCT04712799 on ClinicalTrials.gov

What this trial studies

This study investigates the relationship between nasal breathing and physical capacity in individuals with nasal obstruction and COPD, as well as healthy individuals and athletes. It aims to understand how nasal breathing affects daily activities and exercise performance by examining the upper and lower airway interactions. The intervention involves the use of Otrivin, a nasal decongestant, to assess its effects on physical capacity. The findings could lead to evidence-based decisions regarding medical and surgical interventions to improve nasal airflow and overall physical performance.

Who should consider this trial

Good fit: Ideal candidates include individuals with COPD, nasal obstruction, or those interested in enhancing their physical performance.

Not a fit: Patients with other pulmonary diseases or those who are pregnant may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of nasal breathing's role in improving physical capacity for patients with respiratory conditions and athletes.

How similar studies have performed: While the specific focus on nasal breathing and physical capacity is novel, related studies have shown the importance of airway health in overall physical performance.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

COPD-

Exclusion Criteria:

* Other pulmonary diseases pregnancy

Where this trial is running

Kristiansand, Agder

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Nasal Obstruction, Copd, nose, lungs, physical capacity

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.