Exploring the impact of immunosuppressants on infection and survival after organ transplantation
The Cost-effectiveness Analysis of Immunosuppressants to Postoperative Infection and Death in the Patients With Organ Transplantation
This study looks at how different medications that suppress the immune system affect infection rates and survival in people who have received organ transplants.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 20000 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | Chung Shan Medical University Academic / other |
| Locations | 1 site (Taichung) |
| Trial ID | NCT06121804 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the effects of various immunosuppressive agents on infection rates and survival outcomes in patients who have undergone solid organ transplants in Taiwan. Utilizing secondary data from the Longitudinal Health Insurance Database, the study employs propensity score matching to create a matched cohort for comparison. The research aims to provide real-world evidence that can inform clinical decisions and healthcare policies regarding immunosuppressive therapy in transplant patients.
Who should consider this trial
Good fit: Ideal candidates for this study are patients who have undergone a solid organ transplant, such as kidney, liver, or lung transplants.
Not a fit: Patients who received more than one solid organ transplant or had pre-existing infectious diseases prior to their transplant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of immunosuppressive therapy, potentially leading to improved patient outcomes in organ transplantation.
How similar studies have performed: Other studies have explored the effects of immunosuppressive agents in transplant patients, indicating that this area of research has potential for significant findings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who underwent solid organ transplant (SOT) Exclusion Criteria: * Patients who received more than one SOT, had an infectious disease diagnosis before their SOT or had incomplete medical information in the database.
Where this trial is running
Taichung
- Chung Shan Medical University — Taichung, Taiwan (Recruiting)
Study contacts
- Study coordinator: Chien-Ying Lee, PhD
- Email: cshd015@csmu.edu.tw
- Phone: 886-4-24730022
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.