Exploring the impact of food polyphenols on pancreatic health.
Experimental, Drug-free, Cross-sectional, Single-centre Study to Assess the Association Between Metabotypes of Dietary (Poly)Phenols and Beta-cell Mass and Function.
This study is trying to see how different types of food compounds called polyphenols affect the health of the pancreas in healthy people who have already taken part in a related study.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Azienda Ospedaliero-Universitaria di Parma Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Parma, PR) |
| Trial ID | NCT06888167 on ClinicalTrials.gov |
What this trial studies
This clinical study investigates the relationship between dietary polyphenol metabotypes and pancreatic beta-cell mass and function in healthy volunteers. It builds on previous research that identified individual responses to polyphenol consumption and aims to explore how these responses may affect cardiometabolic health. The study employs a low-risk diagnostic technique and focuses on participants who have previously been enrolled in a related intervention study. By analyzing the metabolic profiles of participants, the study seeks to uncover potential associations that could inform dietary recommendations for improving pancreatic health.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy individuals who have previously participated in the OPCT study and can provide informed consent.
Not a fit: Patients who are pregnant, breastfeeding, or have certain medical conditions such as active neurological diseases or psychiatric illnesses may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to personalized dietary guidelines that enhance pancreatic function and reduce the risk of diabetes.
How similar studies have performed: While this approach builds on previous studies regarding dietary polyphenols, the specific focus on pancreatic beta-cell function in relation to metabotypes is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Having been enrolled in the OPCT study; * Ability to understand the methods, purposes and implications of the study, and to give free and informed consent. Exclusion Criteria: * Pregnancy or breastfeeding; * Previous exposure to ionizing radiation in research programs; * History of psychiatric illness or alcohol abuse; * Head trauma; * Active neurological disease; * Claustrophobia; * Active malignant neoplastic disease.
Where this trial is running
Parma, PR
- Azienda Ospedaliero-Universitaria di Parma — Parma, Pr, Italy (Recruiting)
Study contacts
- Study coordinator: Alessandra Dei Cas, Prof.
- Email: alessandra.deicas@unipr.it
- Phone: +390521033321
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.