Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Exploring the impact of food polyphenols on pancreatic health.

Official title: Experimental, Drug-free, Cross-sectional, Single-centre Study to Assess the Association Between Metabotypes of Dietary (Poly)Phenols and Beta-cell Mass and Function.

Run by Azienda Ospedaliero-Universitaria di Parma · NCT06888167 · Data updated 2026-11-12

This study is trying to see how different types of food compounds called polyphenols affect the health of the pancreas in healthy people who have already taken part in a related study.

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Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment40 (estimated)
SponsorAzienda Ospedaliero-Universitaria di Parma
Academic / other
Drugs / interventionsradiation
Locations1 site (Parma, PR)
StatusRecruiting
StartedOctober 14, 2024
Main results expectedDecember 31, 2025
Study endsFebruary 28, 2026
Registry record updatedMarch 21, 2025
Trial IDNCT06888167 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy individuals who have previously participated in the OPCT study and can provide informed consent.

Probably not a fit

Patients who are pregnant, breastfeeding, or have certain medical conditions such as active neurological diseases or psychiatric illnesses may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical study investigates the relationship between dietary polyphenol metabotypes and pancreatic beta-cell mass and function in healthy volunteers. It builds on previous research that identified individual responses to polyphenol consumption and aims to explore how these responses may affect cardiometabolic health. The study employs a low-risk diagnostic technique and focuses on participants who have previously been enrolled in a related intervention study. By analyzing the metabolic profiles of participants, the study seeks to uncover potential associations that could inform dietary recommendations for improving pancreatic health.

Why it matters

Potential benefit: If successful, this study could lead to personalized dietary guidelines that enhance pancreatic function and reduce the risk of diabetes.

How similar studies have gone: While this approach builds on previous studies regarding dietary polyphenols, the specific focus on pancreatic beta-cell function in relation to metabotypes is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Having been enrolled in the OPCT study;
* Ability to understand the methods, purposes and implications of the study, and to give free and informed consent.

Exclusion Criteria:

* Pregnancy or breastfeeding;
* Previous exposure to ionizing radiation in research programs;
* History of psychiatric illness or alcohol abuse;
* Head trauma;
* Active neurological disease;
* Claustrophobia;
* Active malignant neoplastic disease.

Where it's running

  • Azienda Ospedaliero-Universitaria di Parma
    Parma, Pr, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.