Exploring the impact of food polyphenols on pancreatic health.
Official title: Experimental, Drug-free, Cross-sectional, Single-centre Study to Assess the Association Between Metabotypes of Dietary (Poly)Phenols and Beta-cell Mass and Function.
Run by Azienda Ospedaliero-Universitaria di Parma · NCT06888167 · Data updated 2026-11-12
This study is trying to see how different types of food compounds called polyphenols affect the health of the pancreas in healthy people who have already taken part in a related study.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Azienda Ospedaliero-Universitaria di Parma Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Parma, PR) |
| Status | Recruiting |
| Started | October 14, 2024 |
| Main results expected | December 31, 2025 |
| Study ends | February 28, 2026 |
| Registry record updated | March 21, 2025 |
| Trial ID | NCT06888167 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy individuals who have previously participated in the OPCT study and can provide informed consent.
✕Probably not a fit
Patients who are pregnant, breastfeeding, or have certain medical conditions such as active neurological diseases or psychiatric illnesses may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical study investigates the relationship between dietary polyphenol metabotypes and pancreatic beta-cell mass and function in healthy volunteers. It builds on previous research that identified individual responses to polyphenol consumption and aims to explore how these responses may affect cardiometabolic health. The study employs a low-risk diagnostic technique and focuses on participants who have previously been enrolled in a related intervention study. By analyzing the metabolic profiles of participants, the study seeks to uncover potential associations that could inform dietary recommendations for improving pancreatic health.
Why it matters
Potential benefit: If successful, this study could lead to personalized dietary guidelines that enhance pancreatic function and reduce the risk of diabetes.
How similar studies have gone: While this approach builds on previous studies regarding dietary polyphenols, the specific focus on pancreatic beta-cell function in relation to metabotypes is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Having been enrolled in the OPCT study; * Ability to understand the methods, purposes and implications of the study, and to give free and informed consent. Exclusion Criteria: * Pregnancy or breastfeeding; * Previous exposure to ionizing radiation in research programs; * History of psychiatric illness or alcohol abuse; * Head trauma; * Active neurological disease; * Claustrophobia; * Active malignant neoplastic disease.
Where it's running
-
Azienda Ospedaliero-Universitaria di Parma
Parma, Pr, Italy Recruiting
Study contacts
- Study coordinator: Alessandra Dei Cas, Prof.
- Email: alessandra.deicas@unipr.it
- Phone: +390521033321
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Pfizer medicine PF-08103402: how different doses are tolerated in healthy adults and adults with mild-to-moderate asthma
This study tests how different amounts of PF-08103402 behave in the body and how well it is tolerated by healthy adults and adults with mild-to-moderate asthma.
-
Comparing how three adhesive dressings stay on the skin
We will test how well three different self-adhesive dressings stick to and stay on the back of healthy adults.
-
Focal muscle vibration to limit leg muscle weakness during reduced use
This trial will see if a 10-day program of focal muscle vibration can limit strength loss in healthy adults whose one leg is temporarily unloaded.
-
Kidney responses to exercise in heat and whether vitamin B3 changes them.
This project will test whether taking vitamin B3 changes how the kidneys respond when healthy, physically fit adults exercise in hot, humid conditions.
-
Assessing the safety of inhaling xenon gas in healthy volunteers
This study is testing if inhaling xenon gas is safe for healthy people to see if it could help in treating neurodegenerative diseases like Alzheimer's in the future.
-
Brain responses to gentle ear stimulation measured with near-infrared light
This one-visit test uses gentle ear stimulation and near-infrared head sensors to see how healthy adults' brains respond.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.