Exploring the health benefits of bean supplementation for colorectal health
Feasibility of Pulses Supplementation in Healthy Adults: A Feeding Study
This study is testing whether drinking a bean smoothie for two weeks can improve bowel health and help prevent colon cancer in adults who are getting a colonoscopy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 25 (estimated) |
| Ages | 30 Years to 80 Years |
| Sex | All |
| Sponsor | University of California, Davis Academic / other |
| Locations | 1 site (Sacramento, California) |
| Trial ID | NCT06032104 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of dry bean supplementation on metabolic and bowel health in adults scheduled for a standard colonoscopy. Participants will be randomly assigned to consume a bean smoothie for two weeks alongside their usual diet or to continue their usual diet without the smoothie. The study aims to collect various health data, including breath tests, stool samples, and blood samples, to assess the impact of beans on bowel health and potential prevention of colon cancer. Approximately 25 adults aged 35-75 with overweight or obesity will be involved in this research.
Who should consider this trial
Good fit: Ideal candidates are adults aged 30-80 who are overweight or obese and scheduled for a standard colonoscopy.
Not a fit: Patients with active gastrointestinal diseases, significant systemic conditions, or a history of malignancy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into dietary interventions that improve bowel health and reduce the risk of colon cancer.
How similar studies have performed: While the specific approach of this study is novel, previous studies have indicated potential health benefits of dietary fiber and legumes in colorectal health.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusions: 1. 30-80 years-old 2. Overweight or obesity (body mass index ≥ 25 kg/m2) 3. Planned for a standard of care colonoscopy for colon cancer screening Exclusions: 1. Intolerance to a bean or high bean consumer based on a screening survey 2. Pregnancy or actively planning to get pregnant 3. Any active gastrointestinal disease resulting in disturbed gut function or malabsorption (e.g., chronic diarrhea or inflammatory bowel disease) 4. Current or history of any malignancy in the past 10 years. 5. Chronic use of opioids, anti-inflammatory drugs, antibiotics, prebiotics, or probiotics within 1 month of study endpoints 6. History of a significant systemic condition (e.g., heart disease, chronic kidney disease, liver dysfunction or immune suppression), or abnormal laboratory markers (e.g., abnormal liver enzymes, creatinine, clotting factors, or low platelets count). The severity of the intolerance to fiber/ the medical conditions/lab markers and eligibility will be defined after the careful interview of the patient/review of the medical records by Dr. Hussan)
Where this trial is running
Sacramento, California
- University of California Davis — Sacramento, California, United States (Recruiting)
Study contacts
- Principal investigator: Hisham Hussan, MD — UC Davis
- Study coordinator: Hisham Hussan, MD
- Email: hhussan@ucdavis.edu
- Phone: (916) 734-8246
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.