Clinical trial Recruiting at 1 site Phase 1 Interventional Ages 65 and up

Exploring the effects of writing on health in older adults

Official title: Writing About Experiences and Health in Older Adults II

Run by University of California, Los Angeles · NCT05524597 · Data updated 2026-11-12

This study tests if writing about personal experiences can improve the health and well-being of healthy older adults aged 65 and above.

Quick facts

PhasePhase 1
Study typeInterventional
Ages65 Years and up
SexAll
Enrollment200 (estimated)
SponsorUniversity of California, Los Angeles
Academic / other
Locations1 site (Los Angeles, California)
StatusRecruiting
StartedMarch 13, 2023
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedOctober 15, 2026
Trial IDNCT05524597 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy adults aged 65 years and older.

Probably not a fit

Patients with active medical disorders, psychiatric conditions, or those who are left-handed may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how writing about personal experiences influences the brain and body in healthy older adults aged 65 and above. Participants will engage in a weekly writing intervention for six weeks, during which they will also complete online questionnaires. Additionally, they will undergo neuroimaging sessions and provide blood samples at the beginning and end of the writing period to assess any physiological changes. The study aims to understand the potential health benefits of expressive writing in older populations.

Why it matters

Potential benefit: If successful, this study could enhance mental and physical health outcomes for older adults through therapeutic writing practices.

How similar studies have gone: Previous studies have shown promising results regarding the health benefits of expressive writing, suggesting this approach may be effective.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy adults age 65 years and older

Exclusion Criteria:

1. current smokers
2. active, uncontrolled medical disorders
3. chronic infection (e.g., Hepatitis C, HIV)
4. use of certain medications (steroid use, opioid use)
5. psychiatric disorders (e.g., current major depression, bipolar disorder)
6. body mass index (BMI) greater than 35
7. left-handed
8. claustrophobic
9. metal in body

Other exclusion criteria may apply.

Where it's running

  • Center for Cognitive Neuroscience
    Los Angeles, California, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.