Exploring the effects of postbiotics on elderly hemodialysis patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial investigates the impact of exogenous postbiotics on the quality of life and nutritional status of elderly patients undergoing hemodialysis. Participants aged 65 and older will be randomly assigned to receive either a postbiotics product or a placebo for 12 weeks, followed by a crossover period where the placebo group will receive the postbiotics. The study aims to assess changes in quality of life and nutrition through various indicators over the treatment period. It is a multicenter, prospective, open-label, randomized controlled trial designed to provide insights into the benefits of postbiotics for this vulnerable population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Investigators must maintain a screening log of all potential study candidates that includes limited information about the potential candidate, date, and outcome of the screening process (e.g. enrolled into study, reason for ineligibility, or refused to participate). After signing an informed consent form, potential patients must meet all of the criteria:

1. Age ≥65 years.
2. Receiving maintenance hemodialysis therapy for at least 6 months.

Exclusion Criteria:

The following exclusion criteria must NOT be present for each subject:

1. Subjects with medical history that might affect oral feeding (e.g. intestinal obstruction, gastrointestinal bleeding, acute pancreatitis and accidental inhalation) within the last 1 month prior to screening.
2. Subjects with medical history that might affect gastrointestinal functions (e.g. inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), short bowel syndrome (SBS), et al.).
3. Subjects who cannot communicate and collaborate normally.

Where it's running

• Peking UFH
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Yuqing Chen
• Email: cyq@bjmu.edu.cn
• Phone: 86-010-82572254

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.